Suppr超能文献

6 个月以下住院患儿严重消瘦的 100 天结局。

100 days outcome of severe wasting in hospitalised infants <6 months of age.

机构信息

Department of Pediatrics, University College of Medical Sciences, Associated GTB Hospital, Dilshad Garden, New Delhi110095, India.

出版信息

Public Health Nutr. 2021 Dec;24(17):5847-5856. doi: 10.1017/S1368980021003268. Epub 2021 Aug 6.

Abstract

OBJECTIVE

To assess the outcome of severe wasting in infants below 6 months of age.

DESIGN

A prospective observational study conducted between January 2017 and October 2018.

SETTING

A medical college-affiliated hospital in Eastern Delhi, catering mainly to the urban poor population.

PARTICIPANTS

All children with severe wasting (weight-for-length Z-score (WLZ) < -3 sd) between 1 and 6 months of age, requiring hospitalisation.

RESULTS

Out of fifty children enrolled, during hospitalisation, forty-two (84 %) recovered (WLZ > -3 sd) and discharged; the median (interquartile range (IQR)) duration of stay was 9·5 (6·5, 13·0) d. After 100 d of enrolment, sustained cure (WLZ > -2 SD) could be achieved in only fifteen (30 %) infants, while another fourteen (28 %) recovered from severe wasting, but remained in moderately wasted state (WLZ between -2 and -3 sd). Overall, there were three (6 %) deaths (all during first week of hospitalisation); three (6 %) relapses and fifteen (30 %) defaulters (5, 5, 2, 1 and 2 defaulted during hospitalisation at day 15, day 60, day 75 and day 90, respectively).

CONCLUSIONS

The overall recovery rate from severe wasting in infants below 6 months of age was below the acceptable levels. In order to achieve better long-term outcome, community linkage services after discharge from hospital are required for supervised feeding, close monitoring and supportive care.

摘要

目的

评估 6 月龄以下严重消瘦婴儿的结局。

设计

2017 年 1 月至 2018 年 10 月进行的前瞻性观察性研究。

地点

德里东部一所医学院附属医院,主要为城市贫困人群服务。

参与者

所有 1 至 6 月龄严重消瘦(身长别体重 Z 评分(WLZ)<-3sd)且需要住院的儿童。

结果

50 名入组儿童中,住院期间 42 名(84%)恢复(WLZ>-3sd)并出院;中位(四分位间距(IQR))住院时间为 9.5(6.5,13.0)d。入组后 100d,仅 15 名(30%)婴儿持续治愈(WLZ>-2sd),而另外 14 名(28%)严重消瘦儿童恢复,但仍处于中度消瘦状态(WLZ 在-2 和-3sd 之间)。总共有 3 名(6%)儿童死亡(均在住院第 1 周);3 名(6%)患儿病情复发,15 名(30%)患儿失访(5、5、2、1 和 2 名患儿分别在住院第 15、60、75 和 90d 失访)。

结论

6 月龄以下严重消瘦婴儿的整体恢复率低于可接受水平。为了获得更好的长期结局,需要在出院后提供社区联系服务,以进行监督喂养、密切监测和支持性护理。

相似文献

1
100 days outcome of severe wasting in hospitalised infants <6 months of age.6 个月以下住院患儿严重消瘦的 100 天结局。
Public Health Nutr. 2021 Dec;24(17):5847-5856. doi: 10.1017/S1368980021003268. Epub 2021 Aug 6.
7
Neurodevelopment and Recovery From Wasting.神经发育与消瘦康复。
Pediatrics. 2022 Nov 1;150(5). doi: 10.1542/peds.2021-055615.
8
Wasting is associated with stunting in early childhood.消瘦与儿童早期发育迟缓有关。
J Nutr. 2012 Jul;142(7):1291-6. doi: 10.3945/jn.111.154922. Epub 2012 May 23.

本文引用的文献

4
Outcome of Children with Severe Acute Malnutrition and Diarrhea: a Cohort Study.重度急性营养不良与腹泻患儿的结局:一项队列研究
Pediatr Gastroenterol Hepatol Nutr. 2019 May;22(3):242-248. doi: 10.5223/pghn.2019.22.3.242. Epub 2019 Apr 19.
9
Failure to thrive in babies and toddlers.婴幼儿生长发育迟缓。
Singapore Med J. 2016 Jun;57(6):287-91. doi: 10.11622/smedj.2016102.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验