Ciardetti Niccolò, Ristalli Francesca, Nardi Giulia, Di Mario Carlo
Structural Interventional Cardiology, Department of Clinical and Experimental Medicine, Careggi University Hospital, Clinica Medica, Room 124, Largo Brambilla 3, 50134 Florence, Italy.
Eur Heart J Case Rep. 2021 Nov 11;5(11):ytab448. doi: 10.1093/ehjcr/ytab448. eCollection 2021 Nov.
Intravascular lithotripsy is safe and effective for the treatment of coronary artery calcifications. Its bail-out use in acute coronary syndrome and for underexpanded stents, although currently off-label, could be the best option when other conventional techniques fail.
A patient with an inferior ST-segment elevation myocardial infarction underwent a primary percutaneous coronary intervention. Stent underexpansion due to a heavily calcified lesion was refractory to high-pressure balloon dilatations. Complete stent expansion was achieved with intravascular lithotripsy, as evidenced by intravascular ultrasound, and no acute complications occurred.
Treatment strategies for stent underexpansion due to coronary artery calcifications are still debated. High-pressure non-compliant balloon dilatations are rarely sufficient to gain a complete stent expansion. Rotational and orbital atherectomy are contraindicated in presence of a thrombus. Given the possible risks of stent damages, intravascular lithotripsy is currently not indicated in acutely deployed stents but could be the best bail-out technique for otherwise undilatable stents due to severely calcified plaques.
血管内碎石术治疗冠状动脉钙化安全有效。其在急性冠状动脉综合征及支架扩张不全时的补救应用,尽管目前属于超适应证使用,但在其他传统技术失败时可能是最佳选择。
一名下壁ST段抬高型心肌梗死患者接受了急诊经皮冠状动脉介入治疗。由于病变严重钙化导致支架扩张不全,高压球囊扩张治疗无效。血管内超声显示血管内碎石术使支架完全扩张,且未发生急性并发症。
冠状动脉钙化导致支架扩张不全的治疗策略仍存在争议。高压非顺应性球囊扩张很少能使支架完全扩张。存在血栓时禁忌使用旋磨术和轨道旋切术。鉴于可能存在支架损伤风险,血管内碎石术目前不适用于急性植入的支架,但对于因严重钙化斑块导致无法扩张的支架,可能是最佳的补救技术。