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光照疗法治疗脑卒中后失眠患者的疗效和安全性评价:系统评价和荟萃分析方案。

Efficacy and safety evaluation of bright light therapy in patients with post-stroke insomnia: A protocol for systematic review and meta-analysis.

机构信息

Sun Simiao Hospital, Beijing University of Chinese Medicine, Tongchuan, Shaanxi, China.

出版信息

Medicine (Baltimore). 2021 Dec 17;100(50):e27937. doi: 10.1097/MD.0000000000027937.

Abstract

BACKGROUND

Post-stroke insomnia (PSI) is a common and severe illness among the complications of stroke. Although there are plenty of drugs currently used for PSI treatment, they generate several side effects and other problems. Bright light therapy (BLT) is thought to be relatively safe and effective in treating PSI patients. Despite this, there is still a lack of systematic review on BLT in the treatment of PSI. Allowing for this, the aim of this study is to assess the efficacy and safety of BLT for PSI.

METHODS

The meta-analysis and systematic review will perform a comprehensive electronic search for items fulfilling the required criteria in Web of Science, Google Scholar, Wan Fang database, MEDLINE, Baidu Scholar, PubMed, SinoMed, Embase, Chinese Biomedical Literature Database (CBM), China national knowledge infrastructure database (CNKI), Cochrane Library Central Register of Controlled Trials (CENTRAL), and Wei Pu database from establishment to January 1, 2022. We will select articles, collect data, and assess the methodology quality. And we will set the primary outcome and secondary outcomes in this research. RevMan 5.3 software will be used to analyze the data for this investigation.

RESULTS

The work of this research will be published in peer-reviewed scientific journals.

CONCLUSION

The aim of this study is to assess the efficacy and safety of BLT for PSI and present robust scientific evidence concerning BLT for PSI.

REGISTRATION

INPLASY2021100065.

摘要

背景

中风后失眠(PSI)是中风并发症中一种常见且严重的疾病。尽管目前有许多药物可用于治疗 PSI,但它们会产生一些副作用和其他问题。光疗(BLT)被认为是治疗 PSI 患者相对安全有效的方法。尽管如此,BLT 治疗 PSI 的系统评价仍然缺乏。有鉴于此,本研究旨在评估 BLT 治疗 PSI 的疗效和安全性。

方法

本 meta 分析和系统评价将全面检索 Web of Science、Google Scholar、万方数据库、MEDLINE、百度学术、PubMed、SinoMed、Embase、中国生物医学文献数据库(CBM)、中国知网数据库(CNKI)、Cochrane 图书馆对照试验中心注册库(CENTRAL)和维普数据库中符合纳入标准的研究,检索时间截至 2022 年 1 月 1 日。我们将选择文章、收集数据并评估方法学质量。我们将在本研究中设定主要结局和次要结局。RevMan 5.3 软件将用于分析本研究的数据。

结果

本研究的结果将发表在同行评议的科学期刊上。

结论

本研究旨在评估 BLT 治疗 PSI 的疗效和安全性,并为 BLT 治疗 PSI 提供有力的科学证据。

注册

INPLASY2021100065。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b277/8677890/bddaff09e527/medi-100-e27937-g001.jpg

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