CHU Réunion, service des maladies infectieuses - dermatologie, Saint-Pierre, Reunion.
Inserm CIC1410, CHU Réunion, Saint-Pierre, Reunion.
Infect Dis Now. 2022 May;52(3):149-153. doi: 10.1016/j.idnow.2021.12.003. Epub 2021 Dec 15.
To determine the prevalence and risk factors for gonococcal infection, and the resistance profile of Neisseria gonorrhoeae (NG) in Reunion Island.
All patients who visited the four sexually transmitted infection (STI) clinics of Reunion Island between January 2017 and December 2018 were screened by multiplex polymerase chain reaction. Data on patient characteristics were collected using a self-administered questionnaire (reason for screening, marital status, risk-taking behaviors, place of birth, employment status, type of health care coverage, sexual orientation, number of sexual partners, occurrence of extra-marital relationships, history of STIs, and symptomatology. Precarity was defined as being unemployed and/or receiving universal health insurance).
The prevalence of NG (n=4289) in the screened population was 2.8% (95% CI [2.3-3.3]). Minors were especially at-risk (4.4% (95% CI [2.6-7])) and especially girls (5.6% (95% CI [3.2-8.9])). The prevalence observed in the homosexual population was 4.0% [2.6-5.9]. Gonococcal infection was asymptomatic in 56 (69%) patients. For all infection sites, the main risk factors were male minors (P=0.019), individuals living in conditions of precarity (P=0.023), individuals co-infected with chlamydia (P<0.001) or syphilis (P<0.001), and individuals of foreign origin (P=0.006). No NG strain was resistant to ceftriaxone. Strains were resistant to penicillin G, ciprofloxacin, and azithromycin in 22% (20/91), 38% (35/91), and 1% (1/91) of cases, respectively.
The prevalence of NG in patients visiting STI clinics in Reunion Island is particularly high among minors. Prevention programs targeting this population should be reinforced and screening should be facilitated in school settings.
确定留尼汪岛淋病奈瑟菌（NG）感染的流行率和危险因素，以及耐药谱。
2017 年 1 月至 2018 年 12 月期间，对留尼汪岛的四个性传播感染（STI）诊所的所有患者进行了多重聚合酶链反应筛查。通过自填问卷收集患者特征数据（筛查原因、婚姻状况、冒险行为、出生地、就业状况、医疗保险类型、性取向、性伴侣数量、婚外性关系、性传播感染史和症状）。脆弱性定义为失业和/或接受全民医疗保险。
筛查人群中 NG（n=4289）的流行率为 2.8%（95% CI [2.3-3.3]）。未成年人的风险尤其高（4.4%（95% CI [2.6-7]）），尤其是女孩（5.6%（95% CI [3.2-8.9]））。同性恋人群中观察到的流行率为 4.0%[2.6-5.9]。56 名（69%）患者的感染无症状。对于所有感染部位，主要危险因素是男性未成年人（P=0.019）、生活在脆弱环境中的个体（P=0.023）、同时感染衣原体（P<0.001）或梅毒（P<0.001）的个体以及外国血统的个体（P=0.006）。没有 NG 菌株对头孢曲松耐药。青霉素 G、环丙沙星和阿奇霉素耐药率分别为 22%（20/91）、38%（35/91）和 1%（1/91）。
留尼汪岛 STI 诊所就诊患者中 NG 的流行率在未成年人中特别高。应加强针对这一人群的预防计划，并在学校环境中促进筛查。
