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因意识障碍而在现场插管的患者中,严重创伤性脑损伤的发生率。

Prevalence of significant traumatic brain injury among patients intubated in the field due to impaired level of consciousness.

机构信息

Critical Care Division, Rambam Health Care Campus, HaAliya HaShniya St 8, Haifa 3109601, Israel.

Department of Internal Medicine B, Rambam Health Care Campus, HaAliya HaShniya St 8, Haifa 3109601, Israel.

出版信息

Am J Emerg Med. 2022 Feb;52:159-165. doi: 10.1016/j.ajem.2021.12.015. Epub 2021 Dec 13.

DOI:10.1016/j.ajem.2021.12.015
PMID:34922237
Abstract

OBJECTIVE

Current guidelines advocate prehospital endotracheal intubation (ETI) in patients with suspected severe head injury and impaired level of consciousness. However, the ability to identify patients with traumatic brain injury (TBI) in the prehospital setting is limited and prehospital ETI carries a high complication rate. We investigated the prevalence of significant TBI among patients intubated in the field for that reason.

METHODS

Data were retrospectively collected from emergency medical services and hospital records of trauma patients for whom prehospital ETI was attempted and who were transferred to Rambam Health Care Campus, Israel. The indication for ETI was extracted. The primary outcome was significant TBI (clinical or radiographic) among patients intubated due to suspected severe head trauma.

RESULTS

In 57.3% (379/662) of the trauma patients, ETI was attempted due to impaired consciousness. 349 patients were included in the final analysis: 82.8% were male, the median age was 34 years (IQR 23.0-57.3), and 95.7% suffered blunt trauma. 253 patients (72.5%) had significant TBI. In a multivariable analysis, Glasgow Coma Scale>8 and alcohol intoxication were associated with a lower risk of TBI with OR of 0.26 (95% CI 0.13-0.51, p < 0.001) and 0.16 (95% CI 0.06-0.46, p < 0.001), respectively.

CONCLUSION

Altered mental status in the setting of trauma is a major reason for prehospital ETI. Although most of these patients had TBI, one in four of them did not suffer a significant TBI. Patients with a higher field GCS and those suffering from intoxication have a higher risk of misdiagnosis. Future studies should explore better tools for prehospital assessment of TBI and ways to better define and characterize patients who may benefit from early ETI.

摘要

目的

目前的指南主张对疑似严重头部损伤和意识水平受损的患者进行院前气管插管(ETI)。然而,在院前环境中识别创伤性脑损伤(TBI)患者的能力有限,并且院前 ETI 并发症发生率很高。我们调查了因该原因在现场插管的患者中 TBI 发生率。

方法

从以色列 Rambam 医疗保健校园的急诊医疗服务和创伤患者的医院记录中回顾性收集数据。提取 ETI 的指征。主要结局是因疑似严重头部创伤而接受 ETI 的患者中存在显著 TBI(临床或影像学)。

结果

在 662 名创伤患者中,有 57.3%(379/662)因意识障碍而尝试进行 ETI。最终纳入 349 例患者进行分析:82.8%为男性,中位年龄为 34 岁(IQR 23.0-57.3),95.7%为钝性创伤。253 例患者(72.5%)存在显著 TBI。多变量分析显示,格拉斯哥昏迷量表评分>8 和酒精中毒与 TBI 风险降低相关,OR 分别为 0.26(95%CI 0.13-0.51,p<0.001)和 0.16(95%CI 0.06-0.46,p<0.001)。

结论

创伤患者的精神状态改变是院前 ETI 的主要原因。尽管这些患者大多存在 TBI,但四分之一的患者并未发生显著 TBI。格拉斯哥昏迷量表评分较高和中毒的患者误诊风险更高。未来的研究应探索更好的院前 TBI 评估工具,并寻找更好的方法来定义和描述可能受益于早期 ETI 的患者。

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