Houdek Matthew T, Wellings Elizabeth P, Mallett Katherine E, Honig Rachel L, Rose Peter S, Moran Steven L
Mayo Clinic, Department of Orthopedic Surgery, Rochester, MN, USA.
Mayo Clinic Division of Plastic and Reconstructive Surgery, Rochester, MN, USA.
Sarcoma. 2021 Dec 8;2021:8480737. doi: 10.1155/2021/8480737. eCollection 2021.
Limb-salvage surgery combined with radiotherapy has become the primary treatment for soft tissue sarcomas of the extremity. Free functional latissimus flaps (FFLF) are an option to restore function in the setting of volumetric muscle loss. The purpose of the current study was to examine the use of FFLF in patients undergoing resection of thigh sarcoma.
Twelve patients with a sarcoma involving the hamstring ( = 6), quadriceps ( = 5), or combined ( = 1) defects which included multiple muscle groups were reviewed. This included 9 males and 3 females with a mean age and body mass index of 56 ± 12 years and 31.3 ± 5.7 kg/m.
The mean defect volume and operative time was 3,689 ± 2,314 cm and 587 ± 73 minutes. Following reconstruction, the mean knee range of motion (ROM), MSTS93 score, and muscle strength was 89 ± 24°, 90 ± 15%, and 4 ± 1; with 75% of patients ambulating without gait aids. Seven (58%) patients sustained a complication, namely, delayed wound healing ( = 2).
Although there was a high incidence of complications, FFLF can restore active knee ROM and function, with most patients ambulating without gait aids following reconstruction of large oncologic defects in the thigh.
保肢手术联合放疗已成为肢体软组织肉瘤的主要治疗方法。游离功能性背阔肌肌皮瓣(FFLF)是在肌肉容量缺失情况下恢复功能的一种选择。本研究的目的是探讨FFLF在大腿肉瘤切除患者中的应用。
回顾了12例患有累及腘绳肌(n = 6)、股四头肌(n = 5)或两者合并(n = 1)缺损(包括多个肌肉群)的肉瘤患者。其中包括9名男性和3名女性,平均年龄和体重指数分别为56 ± 12岁和31.3 ± 5.7kg/m²。
平均缺损体积和手术时间分别为3689 ± 2314cm³和587 ± 73分钟。重建后,平均膝关节活动范围(ROM)、MSTS93评分和肌肉力量分别为89 ± 24°、90 ± 15%和4 ± 1;75%的患者无需借助助行器行走。7例(58%)患者出现并发症,即伤口愈合延迟(n = 2)。
尽管并发症发生率较高,但FFLF可恢复膝关节的主动活动范围和功能,大多数患者在大腿巨大肿瘤缺损重建后无需借助助行器行走。