男性 Graves 病合并甲状腺微小乳头状癌 1 例报告并文献复习
Papillary thyroid microcarcinoma in a boy with Graves' disease: a case report and review of the literature.
机构信息
Department of Pediatric Endocrinology, Regina Margherita Children's Hospital, Turin, Italy.
Department of Public Health and Pediatric Sciences, University of Turin, Italy.
出版信息
Pediatr Endocrinol Diabetes Metab. 2022;28(1):88-90. doi: 10.5114/pedm.2021.107725.
A 16-years old boy with diagnosis of Grave's disease was treated with methimazole for one year before radical total thyroidectomy treatment due to persistence of clinical hormonal hyperthyroidism. Histological analysis revealed the presence of a papillary microcarcinoma. The management of Grave's disease in pediatric age is still under discussion. Therefore, close monitoring of the disease is required, as well as case-by-case tailored decision on how to manage treatment and when to perform the radical one, taking into account the association of Grave's disease with differentiated thyroid cancer in adults and the higher malignancy of thyroid cancer in childhood.
一位 16 岁男孩被诊断患有 Graves 病，在接受放射性碘治疗之前，曾使用甲巯咪唑治疗了一年，但由于临床甲状腺功能亢进症持续存在，故进行了根治性全甲状腺切除术。组织学分析显示存在甲状腺乳头状微小癌。儿科 Graves 病的治疗仍存在争议。因此，需要密切监测疾病，并且需要根据具体情况制定治疗管理决策，以及何时进行根治性手术，需要考虑到成人 Graves 病与分化型甲状腺癌的相关性以及儿童甲状腺癌的更高恶性程度。
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