Otolaryngology Division, Sassari University Hospital, Sassari, Italy.
Unit of Respiratory disease, Sassari University Hospital, Sassari, Italy.
Acta Otorhinolaryngol Ital. 2021 Dec;41(6):544-549. doi: 10.14639/0392-100X-N1361.
The relationship between chronic rhinosinusitis, asthma and allergic rhinitis is well known, but only recently has the scientific community started to evaluate these as different manifestations of a common pathogenic phenomenon, considering them as a unified airway disease.
Twenty-two patients with chronic rhinosinusitis treated with endoscopic sinus surgery (ESS) were included in the study. Sino-nasal assessment questionnaire (SNAQ) investigating subjective evaluation of sino-nasal state was administered to patients, while objective evaluations included nasal endoscopy, sinonasal CT, skin prick tests, nasal cytology, spirometry, bronchodilator responsiveness testing and sputum eosinophil count. All tests were performed before surgery. Two months after surgery, SNAQ questionnaire, nasal endoscopy, spirometry and bronchodilator responsiveness testing were repeated.
All patients had significant improvement of subjective status: mean SNAQ score decreased in all from 99.31 to 16.04. Mean Forced Expiratory Volume in the 1 second (FEV) significantly improved after surgery from 3.23 to 3.45 L/s.
ESS achieved a beneficial effect on upper and lower airway status in patients with chronic rhinosinusitis with or without lower airway diseases.
慢性鼻-鼻窦炎、哮喘和变应性鼻炎之间的关系是众所周知的，但直到最近，科学界才开始将这些视为同一发病机制的不同表现，将其视为一种统一的气道疾病。
本研究纳入了 22 例接受内镜鼻窦手术（ESS）治疗的慢性鼻-鼻窦炎患者。采用鼻-鼻窦炎评估问卷（SNAQ）对患者进行主观评估，同时进行客观评估，包括鼻内镜检查、鼻窦 CT、皮肤点刺试验、鼻细胞学检查、肺功能检查、支气管扩张剂反应性测试和痰嗜酸性粒细胞计数。所有测试均在手术前进行。术后 2 个月，重复 SNAQ 问卷、鼻内镜检查、肺功能检查和支气管扩张剂反应性测试。
所有患者的主观状态均有显著改善：SNAQ 评分均值从 99.31 分降至 16.04 分。术后 1 秒用力呼气容积（FEV）均值从 3.23 升至 3.45 L/s。
ESS 对伴有或不伴有下呼吸道疾病的慢性鼻-鼻窦炎患者的上、下呼吸道状况均有有益的影响。
