Department of Gastroenterology & Hepatology, Amsterdam Gastroenterology and Metabolism, University Medical Centers Amsterdam, Amsterdam, the Netherlands.
Am J Gastroenterol. 2022 Feb 1;117(2):346-351. doi: 10.14309/ajg.0000000000001588.
The aim of this study was to investigate the effect of spontaneous sleep positions on the occurrence of nocturnal gastroesophageal reflux.
In patients referred for ambulatory pH-impedance reflux monitoring, the concurrent sleep position was measured using a sleep position measurement device (measuring left, right, supine, and prone positions).
Fifty-seven patients were included. We observed a significantly shorter acid exposure time in the left (median 0.0%, P25-P75, 0.0%-3.0%), compared with the right lateral position (median 1.2%, 0.0%-7.5%, P = 0.022) and the supine position (median 0.6%, 0.00%-8.3%, P = 0.022). The esophageal acid clearance time was significantly shorter in the left lateral decubitus position (median 35 seconds, 16-115 seconds), compared with the supine (median 76 seconds, 22-257 seconds, P = 0.030) and right lateral positions (median 90 seconds, 26-250 seconds, P = 0.002).
The left lateral decubitus position is associated with significantly shorter nocturnal esophageal acid exposure time and faster esophageal acid clearance compared with the supine and right lateral decubitus positions (see visual abstract).
本研究旨在探讨自发性睡眠体位对夜间胃食管反流发生的影响。
在接受动态 pH 阻抗反流监测的患者中，使用睡眠体位测量装置（测量左侧、右侧、仰卧位和俯卧位）同时测量睡眠体位。
共纳入 57 例患者。与右侧卧位（中位数 1.2%，0.0%-7.5%，P=0.022）和仰卧位（中位数 0.6%，0.00%-8.3%，P=0.022）相比，我们观察到左侧卧位的酸暴露时间明显缩短（中位数 0.0%，P25-P75，0.0%-3.0%）。左侧卧位时食管酸清除时间明显短于仰卧位（中位数 35 秒，16-115 秒）和右侧卧位（中位数 76 秒，22-257 秒，P=0.030）。
与仰卧位和右侧卧位相比，左侧卧位与夜间食管酸暴露时间明显缩短和食管酸清除速度加快相关（见图）。
