Academic Unit of Serra Talhada, Federal Rural University of Pernambuco, Serra Talhada, Pernambuco, Brazil.
J Pharm Pharmacol. 2022 Jun 9;74(6):793-799. doi: 10.1093/jpp/rgab163.
Numerous natural products, including rhamnetin, have been studied in recent years owing to the need for new herbal remedies to treat different illnesses. This study aimed to review the salient properties of rhamnetin and its pharmacological potential and possible toxicological effects.
A search carried out in the ScienceDirect database using the term 'rhamnetin' yielded 573 articles published between 1977 and 2021. However, only those studies that mentioned pharmacological activity of rhamnetin were included in this study. As a result of this selection process, this study included reports that describe rhamnetin as a secondary metabolite with several pharmacological properties.
Rhamnetin (2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one) is a secondary metabolite, belonging to the flavonoid class, present in various plants and fruits; it has different pharmacological properties, including antioxidant, anticancer, anti-inflammatory, antiviral and antibacterial activity. However, conclusive results on the toxicology of rhamnetin have not been reported yet. Therefore, further research is needed to gather detailed information about the effects of rhamnetin.
由于需要新的草药疗法来治疗不同的疾病，近年来许多天然产物，包括鼠李素，都受到了研究。本研究旨在综述鼠李素的显著特性及其药理学潜力和可能的毒理学效应。
在 ScienceDirect 数据库中使用术语“鼠李素”进行搜索，共获得 1977 年至 2021 年期间发表的 573 篇文章。然而，本研究仅纳入了提到鼠李素药理学活性的研究。经过这样的选择过程，本研究纳入了描述鼠李素作为具有多种药理学特性的次生代谢物的报告。
鼠李素（2-(3,4-二羟基苯基)-3,5-二羟基-7-甲氧基色原酮-4-酮）是一种次生代谢物，属于类黄酮类，存在于各种植物和水果中；它具有多种药理学特性，包括抗氧化、抗癌、抗炎、抗病毒和抗菌活性。然而，目前尚未报道关于鼠李素毒理学的明确结果。因此，需要进一步研究以收集关于鼠李素影响的详细信息。
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