与先用0.5%三氯生进行外科手消毒后再用70%酒精溶液相比，单用0.5%三氯生进行外科手消毒对减少细菌载量的影响。

Effect on the reduction of bacterial load after surgical hand antisepsis with triclosan 0.5% compared to triclosan 0.5% followed by 70% alcoholic solution.

作者信息

Santé Luis, Gómez-Lus María Luisa, Martin-Villa Carlos, Becerro-de-Bengoa-Vallejo Ricardo, Alou Luis, Sevillano David

机构信息

Servicio de Anestesiología y Reanimación, Hospital Clínico San Carlos, Universidad Complutense, Madrid, Spain.

Área de Microbiología, Departamento de Medicina, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.

出版信息

Infect Control Hosp Epidemiol. 2023 Mar;44(3):517-519. doi: 10.1017/ice.2021.506. Epub 2021 Dec 22.

DOI:10.1017/ice.2021.506

PMID:34933701

Abstract

Triclosan 0.5% by scrubbing does not meet the UNE-EN12791 criteria to be used in the surgical hand preparation (SHP). Triclosan 0.5% by scrubbing followed by ethanol 70% hand rubbing is suitable without the additional characteristic of sustained effect. This limited effectiveness implies that triclosan should be avoided in SHP given the restrictions on its use in consumer antiseptic products. The trial was registered at ClinicalTrials.gov (ID: NCT04538365).

摘要

通过刷洗使用0.5%的三氯生不符合UNE-EN12791标准用于外科手消毒（SHP）。通过刷洗使用0.5%的三氯生，随后进行70%乙醇擦手是合适的，但不具有持续效果这一额外特性。这种有限的有效性意味着鉴于其在消费用抗菌产品中的使用限制，在外科手消毒中应避免使用三氯生。该试验已在ClinicalTrials.gov注册（ID：NCT04538365）。