胆汁反流性胃炎：治疗性胆道干预后的患病率及危险因素：一项回顾性队列研究。
Bile reflux gastropathy: Prevalence and risk factors after therapeutic biliary interventions: A retrospective cohort study.
作者信息
Othman Amira A A, Dwedar Amal A Z, ElSadek Hany M, AbdElAziz Hesham R, Abdelrahman Abeer A F
机构信息
Department of Internal Medicine, Faculty of Medicine, Suez University, Suez, Egypt.
Department of Internal Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
出版信息
Ann Med Surg (Lond). 2021 Dec 6;72:103168. doi: 10.1016/j.amsu.2021.103168. eCollection 2021 Dec.
BACKGROUND
Bile reflux gastropathy is caused by the backward flow of duodenal fluid into the stomach. A retrospective cohort study was performed to declare if the therapeutic biliary interventions cause bile reflux gastropathy, and to estimate its prevalence and risk factors, and to evaluate the gastric mucosa endoscopic and histopathologic changes.
METHODS
62 patients, with epigastric pain and/or dyspeptic symptoms, were grouped into, : (34) patients that had undergone cholecystectomy and : (28) patients who had undergone at least one of the following procedures for the treatment of benign pathology: endoscopic sphincterotomy and endoscopic stenting. Their ages ranged from 27 to 59 years. All participants had undergone gastroscopy for gastric aspirate analysis as well as gastric mucosa biopsy for histopathological examination.
RESULTS
the prevalence of bile reflux gastropathy was (21.34%) after therapeutic biliary interventions with a -value of 0.000. In both groups, diabetes, obesity, increased gastric bilirubin, and increased gastric pH were risk factors for bile reflux gastropathy , while age, sex, epigastric pain, heartburn, vomiting were mot.
CONCLUSION
bile reflux gastropathy is common after therapeutic biliary interventions being more among obese and diabetic patients.
背景
胆汁反流性胃炎是由十二指肠液反流至胃引起的。进行了一项回顾性队列研究，以确定治疗性胆道干预是否会导致胆汁反流性胃炎，估计其患病率和危险因素，并评估胃黏膜的内镜和组织病理学变化。
方法
62例有上腹部疼痛和/或消化不良症状的患者被分为两组：A组（34例）接受了胆囊切除术；B组（28例）接受了至少一项以下治疗良性病变的手术：内镜括约肌切开术和内镜支架置入术。他们的年龄在27至59岁之间。所有参与者均接受了胃镜检查以进行胃抽吸物分析以及胃黏膜活检以进行组织病理学检查。
结果
治疗性胆道干预后胆汁反流性胃炎的患病率为21.34%，P值为0.000。在两组中，糖尿病、肥胖、胃胆红素升高和胃pH值升高是胆汁反流性胃炎的危险因素，而年龄、性别、上腹部疼痛、烧心、呕吐则不是。
结论
治疗性胆道干预后胆汁反流性胃炎很常见，在肥胖和糖尿病患者中更为多见。
Zotero 插件