发展中国家老年慢性病患者血红蛋白与血压水平的关系：一项社区层面的比较横断面研究
Relationship Between Hemoglobin and Blood Pressure Levels in the Context of Chronic Morbidity Among Older Adults Residing in a Developing Country: A Community-Level Comparative Cross-Sectional Study.
作者信息
Ghosh Tandra, Rehman Tanveer, Ahamed Farhad
机构信息
Physiology, All India Institute of Medical Sciences, Kalyani, Kalyani, IND.
Community Medicine and Family Medicine, All India Institute of Medical Sciences, Kalyani, Kalyani, IND.
出版信息
Cureus. 2021 Nov 13;13(11):e19540. doi: 10.7759/cureus.19540. eCollection 2021 Nov.
OBJECTIVES
The objective of this study is to assess the association between hemoglobin (Hb) and blood pressure (BP) levels among community-dwelling older adults.
MATERIALS AND METHODS
This comparative cross-sectional study was conducted in April 2021 in West Bengal, India. Individuals who are receiving treatment for hypertension, or had a history of blood transfusion, or had a history of intake of iron and vitamins were excluded from the study. A total of 81 and 106 individuals were recruited in "Group 1" (no self-reported comorbidity) and "Group 2" (self-reported comorbidity present), respectively.
RESULTS
The mean (SD) age of the participants (n = 187) was 67.4 (7.4) years; 54% (n = 101) were males; and 45.4% (n = 85) were obese. We found a significant association of Hb level with systolic blood pressure (SBP) (r = 0.22, p = 0.04) and mean arterial pressure (MAP) (r = 0.22, p = 0.04) in "Group 1". The quantum of increases in SBP, diastolic blood pressure (DBP), pulse pressure (PP), and MAP with one gram/dl change in Hb level were 3.24 (95% CI: -0.75 to 7.24) mmHg, 1.17 (95% CI: -0.84 to 3.20) mmHg, 2.06 (95% CI: -0.67 to 4.81) mmHg, and 1.87 (95% CI: -0.65 to 4.39) mmHg, respectively, in "Group 1" after adjustment for age, gender, and body mass index. The findings were inconsistent in "Group 2", and the changes in Hb level were 0.5 (95% CI: -3.77 to 2.77) mmHg, 0.92 (95% CI: -0.72 to 2.75) mmHg, -1.42 (95% CI: -4.09 to 1.24) mmHg, and 0.45 (95% CI: -1.05 to 2.40) mmHg, respectively.
CONCLUSION
Hb level has a positive correlation with SBP and MAP only in those without comorbidities.
目的
本研究的目的是评估社区居住的老年人中血红蛋白（Hb）与血压（BP）水平之间的关联。
材料与方法
这项比较性横断面研究于2021年4月在印度西孟加拉邦进行。正在接受高血压治疗、有输血史或有铁和维生素摄入史的个体被排除在研究之外。“第1组”（无自我报告的合并症）和“第2组”（存在自我报告的合并症）分别招募了81名和106名个体。
结果
参与者（n = 187）的平均（标准差）年龄为67.4（7.4）岁；54%（n = 101）为男性；45.4%（n = 85）为肥胖者。我们发现“第1组”中Hb水平与收缩压（SBP）（r = 0.22，p = 0.04）和平均动脉压（MAP）（r = 0.22，p = 0.04）之间存在显著关联。在调整年龄、性别和体重指数后，“第1组”中Hb水平每变化1克/分升，SBP、舒张压（DBP）、脉压（PP）和MAP的增加量分别为3.24（95%CI：-0.75至7.24）mmHg、1.17（95%CI：-0.84至3.20）mmHg、2.06（95%CI：-0.67至4.81）mmHg和1.87（95%CI：-0.65至4.39）mmHg。“第2组”的结果不一致，Hb水平的变化分别为0.5（95%CI：-3.77至2.77）mmHg、0.92（95%CI：-0.72至2.75）mmHg、-1.42（95%CI：-4.09至1.24）mmHg和0.45（95%CI：-1.05至2.40）mmHg。
结论
Hb水平仅在无合并症的人群中与SBP和MAP呈正相关。
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