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认识库尼斯综合征:2型库尼斯综合征病例报告及治疗简要综述

Recognizing Kounis Syndrome: A Report of Type 2 Kounis Syndrome and a Brief Review of Management.

作者信息

Clemen Britney, Nwosu Ifeanyi, Chukwuka Nnamdi, Cordeiro Nikhil L, Ibeson Emeka, Gulati Amit, Ayzenberg Sergey, Weindorf Benjamin

机构信息

Internal Medicine, Maimonides Medical Center, New York City, USA.

Cardiology, Maimonides Medical Center, New York City, USA.

出版信息

Cureus. 2021 Nov 18;13(11):e19712. doi: 10.7759/cureus.19712. eCollection 2021 Nov.

Abstract

Kounis syndrome is an underdiagnosed medical condition and represents acute coronary syndrome in the setting of allergic reaction. With the increasing prevalence of allergic reactions, more cases of Kounis syndrome are being reported in the literature. Recognizing patients with acute coronary syndrome during an episode of anaphylaxis may be difficult due to symptom overlap; hence, a high index of suspicion must be maintained. This is vital as the management of Kounis syndrome requires meticulous use of medications as some pharmacological agents beneficial to acute coronary syndrome may be detrimental for the ongoing anaphylaxis and vice versa. We report a case of type 2 variant of Kounis syndrome following severe anaphylaxis to nuts to highlight the need for clinicians to suspect Kounis syndrome when managing patients with anaphylaxis and chest symptoms.

摘要

库尼斯综合征是一种诊断不足的病症,表现为在过敏反应背景下的急性冠状动脉综合征。随着过敏反应患病率的增加,文献中报道的库尼斯综合征病例越来越多。由于症状重叠,在过敏反应发作期间识别急性冠状动脉综合征患者可能很困难;因此,必须保持高度的怀疑指数。这至关重要,因为库尼斯综合征的治疗需要谨慎使用药物,因为一些对急性冠状动脉综合征有益的药物可能对正在进行的过敏反应有害,反之亦然。我们报告一例因坚果严重过敏反应后发生的2型变异库尼斯综合征病例,以强调临床医生在治疗有过敏反应和胸部症状的患者时怀疑库尼斯综合征的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6deb/8684398/2ab6ac290bab/cureus-0013-00000019712-i01.jpg

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