Chen Sheng, Chen Mingjue, Wu Xiaohao, Lin Sixiong, Tao Chu, Cao Huiling, Shao Zengwu, Xiao Guozhi
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Department of Biochemistry, School of Medicine, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, 518055, China.
J Orthop Translat. 2021 Sep 10;32:49-58. doi: 10.1016/j.jot.2021.07.005. eCollection 2022 Jan.
To comprehensively analyze the global level and trends of prevalence, incidence and years lived with disability (YLDs) for low back pain (LBP) from 1990 to 2019 by age, sex and sociodemographic index (SDI).
Publicly available modelled data and methods were obtained from the Global Burden of Diseases (GBD) study 2019, and used to evaluate the global burden of LBP through a systematic analysis.
Globally, the age-standardized prevalence, incidence and YLDs rate of LBP were slightly decreased from 1990 to 2019, but the number of the prevalent cases, incident cases and YLDs had substantially increased, and LBP remains the leading cause of YLDs in 2019 worldwide. The number of prevalent cases was increased with age and peaked at the age of 45-54 years for both sexes, and the global prevalence rate was higher in females than in males and increased with age, peaking at the 80-84 age group in both sexes in 2019. Overall, a positive association between the age-standardized YLD rate and SDI was observed over the past thirty years. At the national revel, the United States, Denmark and Switzerland had the three highest levels of age-standardized prevalence, while Zambia, Zimbabwe and Canada showed the highest increase in the age-standardized prevalence during 1990-2019.
LBP is a major public health issue globally, and its burden remains high. Increasing population awareness about its risk factors and preventive measures for LBP are needed to reduce the future burden of this condition.
Due to the high prevalence and heavy burden of LBP globally, it is important to update its epidemiological data. This systematic analysis provides researchers and healthcare policy makers with up-to-date, comprehensive and comparable information on global LBP burden, which is of clinical translational significance.
全面分析1990年至2019年期间，按年龄、性别和社会人口学指数（SDI）划分的全球腰痛（LBP）患病率、发病率和伤残调整生命年（YLDs）水平及趋势。
从《2019年全球疾病负担》（GBD）研究中获取公开可用的模型数据和方法，并通过系统分析来评估LBP的全球负担。
在全球范围内，1990年至2019年期间，LBP的年龄标准化患病率、发病率和YLDs率略有下降，但患病例数、新发病例数和YLDs数大幅增加，并且LBP在2019年仍是全球YLDs的主要原因。患病例数随年龄增加而增多，男女均在45 - 54岁达到峰值，全球患病率女性高于男性且随年龄增长，在2019年男女均在80 - 84岁年龄组达到峰值。总体而言，在过去三十年中观察到年龄标准化YLD率与SDI之间呈正相关。在国家层面，美国、丹麦和瑞士的年龄标准化患病率处于最高的三个水平，而赞比亚、津巴布韦和加拿大在1990 - 2019年期间年龄标准化患病率增长幅度最大。
LBP是全球主要的公共卫生问题，其负担仍然很高。需要提高人群对LBP危险因素及其预防措施的认识，以减轻未来这种疾病的负担。
由于全球LBP患病率高且负担沉重，更新其流行病学数据很重要。这项系统分析为研究人员和卫生保健政策制定者提供了有关全球LBP负担的最新、全面且可比的信息，具有临床转化意义。
