[In vivo study in healthy volunteers on the effect of tetracycline and cotrimoxazole on chemiluminescence and granulocyte adhesion].

The influence of tetracycline and cotrimoxazole on polymorphonuclear leukocyte (PMNL) chemiluminescence and adherence to nylon was investigated in vivo on healthy volunteers. A significant impairment of chemiluminescence and (although not statistically significant) an inhibitory effect on adherence to nylon was observed in subjects receiving tetracycline. Cotrimoxazole did not appear to have a significant influence on PMNL function.