Garbe C, Bertz J, Orfanos C E
Z Hautkr. 1986 Dec 15;61(24):1751-64.
Based on official statistics of causes of deaths and data from regional cancer registers as well as clinical epidemiological data from our clinic, incidence and mortality of malignant melanoma of the skin (MM) in Germany has been analysed. Between 1970 and 1980, the mortality rate of MM according to age rose by 20% for both men and women; the regional incidence in the Saarland, for example, increased by more than 50% (men: 3.4 to 4.6; women: 3.2 to 6.0 per 100,000 inhabitants a year). The earlier development of the MM mortality can be estimated by analysing the mortality of skin cancers in general. In the age groups between 30 and 69 years, the skin cancer mortality was nearly exclusively caused by MM; the mortality rates according to age increased between 1955 and 1980 by more than 100% for men and by more than 75% for women. According to all available data, the MM incidence in West Germany in 1980 was estimated to be 5 per 100,000 inhabitants for men and 8 per 100,000 inhabitants for women. Assuming a continuous increase of incidences, we expect 5,500 new MM cases in 1985.
基于官方死因统计、地区癌症登记数据以及我们诊所的临床流行病学数据,对德国皮肤恶性黑色素瘤(MM)的发病率和死亡率进行了分析。1970年至1980年间,MM的死亡率按年龄计算,男性和女性均上升了20%;例如,萨尔州的地区发病率增加了50%以上(男性:从每10万居民每年3.4例增至4.6例;女性:从每10万居民每年3.2例增至6.0例)。通过分析一般皮肤癌的死亡率,可以估算出MM死亡率的早期发展情况。在30至69岁年龄组中,皮肤癌死亡率几乎完全由MM导致;1955年至1980年间,按年龄计算的死亡率男性增加了100%以上,女性增加了75%以上。根据所有可得数据,1980年西德MM的发病率估计为男性每10万居民5例,女性每10万居民8例。假设发病率持续上升,预计1985年将有5500例新的MM病例。