Chen L, Xie W G, Yu G
Department of Burns, Tongren Hospital of Wuhan University＆Wuhan Third Hospital, Wuhan 430060, China.
Zhonghua Shao Shang Za Zhi. 2021 Dec 20;37(12):1191-1193. doi: 10.3760/cma.j.cn501120-20200801-00366.
On July 11, 2018, a 26 years old male patient with pseudotumor of lower extremity combined with protracted infectious skin ulcer induced by severe hemophilia A was admitted to Tongren Hospital of Wuhan University＆Wuhan Third Hospital. After treatment of supplementary of clotting factors, prothrombin complex, debridement, and vacuum sealing drainage, skin grafting was performed after granulation tissue formation in wounds. After surgery, clotting factor supplement, anti-infection, prevention of hematoma, and so on were performed. The wounds were finally closed with the survival of skin graft, which dramatically improves the patient's quality of life. This case suggests that aggressive and effective surgical treatment can significantly improve the prognosis of patients with severe hemophilia A.
2018年7月11日，一名26岁男性患者因重度甲型血友病合并下肢假肿瘤及迁延不愈的感染性皮肤溃疡入住武汉大学同仁医院暨武汉市第三医院。在补充凝血因子、凝血酶原复合物、清创及负压封闭引流治疗后，待创面形成肉芽组织后行植皮手术。术后进行凝血因子补充、抗感染、预防血肿等处理。最终创面愈合，植皮存活，患者生活质量得到显著改善。该病例提示，积极有效的手术治疗可显著改善重度甲型血友病患者的预后。
