Department of Ophthalmology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
Department of Radiology, Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
Indian J Ophthalmol. 2022 Jan;70(1):302-305. doi: 10.4103/ijo.IJO_1511_21.
Rhino-orbital mucormycosis has seen a huge resurgence in patients post COVID-19 infection. In patients with minimal orbital disease and especially with preserved vision, retrobulbar injections of amphotericin B can be of great help in controlling the disease. Instead of giving daily injections of amphotericin B using needles every time, we used an 18-gauge intravenous (IV) cannula with injection port and suture holes to deliver the amphotericin into the orbital space for a period of 5 days. Patients were more compliant and less distressed with this method compared with being given an injection with a needle daily. We got a good response in terms of orbital disease regression with this method. In our review of the literature, we did not come across any such case of amphotericin B injection using an IV cannula. Injection of amphotericin B into the orbit using an IV cannula is a viable and easy treatment option for cases of rhino-orbital mucormycosis.
COVID-19 感染后，发生 rhino-orbital mucormycosis 的患者数量急剧增加。对于仅有轻微眼眶疾病的患者，特别是视力保存的患者，球后注射两性霉素 B 有助于控制疾病。我们使用带有注射端口和缝线孔的 18 号静脉（IV）套管针代替每天使用针进行两性霉素 B 注射，将两性霉素注入眼眶空间 5 天。与每天注射针相比，患者对此方法的依从性更高，痛苦也更少。我们通过这种方法在眼眶疾病消退方面取得了良好的效果。在我们对文献的回顾中，没有发现任何使用 IV 套管针注射两性霉素 B 的病例。使用 IV 套管针向眼眶内注射两性霉素 B 是 rhino-orbital mucormycosis 的一种可行且简便的治疗选择。
