Bertoni P D, Morandi G
Acta Cardiol. 1987;42(1):1-10.
To study diastolic function we digitized M-mode echocardiograms in 18 acromegalic patients (A) and compared them to an age matched control population (C). Wall thickness and left ventricular (LV) mass index are frankly increased in A (p less than 0.001). Filling pattern of the LV shows in A a prolongation of the isovolumic relaxation period (IRP) (p less than 0.001), an increase of the percentage dimension change of LV during IRP (p less than 0.001) and a reduction of the percentage dimension change during the rapid filling period (p less than 0.01). Our results indicate that relaxation is abnormal in A; this abnormality should be interpreted as a mere consequence of LV hypertrophy.
为研究舒张功能，我们对18例肢端肥大症患者（A组）的M型超声心动图进行了数字化处理，并将其与年龄匹配的对照组人群（C组）进行比较。A组的室壁厚度和左心室（LV）质量指数明显增加（p<0.001）。A组LV的充盈模式显示等容舒张期（IRP）延长（p<0.001），IRP期间LV尺寸变化百分比增加（p<0.001），快速充盈期尺寸变化百分比降低（p<0.01）。我们的结果表明，A组的舒张功能异常；这种异常应仅被解释为LV肥厚的结果。
