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用联合菌苗未能在兔中诱导出对坏死梭杆菌和化脓棒状杆菌混合感染的有效免疫力。

Failure to induce in rabbits effective immunity to a mixed infection of Fusobacterium necrophorum and Corynebacterium pyogenes with a combined bacterin.

作者信息

Cameron C M, Fuls W J

出版信息

Onderstepoort J Vet Res. 1977 Dec;44(4):253-5.

PMID:349444
Abstract

Failure to induce in rabbits effective immunity to a mixed infection of Fusobacterium necrophorum and Corynebacterium pyogenes with a combined bacterin. Onderstepoort Journal of Veterinary Research, 44 (4), 253--2;6 (1977). Rabbits were immunized with alum-precipitated, oil adjuvant and an untreated bacterin composed of F. necrophorum and C. pyogenes. Immunized rabbits were challenged intradermally with a mixture of F. necrophorum and C. pyrogenes. Immunized rabbits were challenged intradermally with a mixture of F. necorphorum and C. pyrogenes. Initially a low level of initial transient resistance could be demonstrated but a solid immunity could not be established.

摘要

用联合菌苗未能使家兔对坏死梭杆菌和化脓棒状杆菌混合感染产生有效免疫力。《 Onderstepoort兽医研究杂志》,44(4),253 - 256(1977年)。用由坏死梭杆菌和化脓棒状杆菌组成的明矾沉淀菌苗、油佐剂菌苗及未处理菌苗对家兔进行免疫。对免疫后的家兔皮内注射坏死梭杆菌和化脓棒状杆菌的混合物进行攻毒。最初可证明有低水平的初始短暂抵抗力,但未能建立牢固的免疫力。

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