Tesarik Jan
MARGen Clinic, Camino de Ronda 2, 18006 Granada, Spain.
Biomedicines. 2021 Dec 17;9(12):1933. doi: 10.3390/biomedicines9121933.
Treatment with antioxidants is increasingly used to slow down aging processes in different organs of the human body, including those implicated in female fertility. There is a plethora of different natural, synthetic or semi-synthetic medicines available on the market; most of them can be purchased without medical prescription. Even though the use of antioxidants, even under conditions of auto-medication, was shown to improve many functions related to female infertility related to oxidative stress, the lack of medical control and supervision can lead to an overmedication resulting in an opposite extreme, reductive stress, which can be counterproductive with regard to reproductive function and produce various adverse health effects in general. This paper reviews the current knowledge relative to the effects of different antioxidants on female reproductive function. The persisting gaps in this knowledge are also highlighted, and the need for medical supervision and personalization of antioxidant prescription is underscored.
抗氧化剂疗法越来越多地用于减缓人体不同器官的衰老过程，包括与女性生育相关的器官。市场上有大量不同的天然、合成或半合成药物；其中大多数无需医生处方即可购买。尽管使用抗氧化剂，即使是在自我药疗的情况下，已被证明可以改善许多与氧化应激相关的女性不孕症相关功能，但缺乏医疗控制和监督可能导致用药过量，从而导致相反的极端情况，即还原应激，这可能对生殖功能产生适得其反的效果，并总体上产生各种不良健康影响。本文综述了关于不同抗氧化剂对女性生殖功能影响的现有知识。还强调了这方面知识中仍然存在的差距，并强调了医疗监督和抗氧化剂处方个性化的必要性。
