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1型糖尿病患者身体活动水平与健康相关生活质量的关联:一项初步研究

Association between the Level of Physical Activity and Health-Related Quality of Life in Type 1 Diabetes Mellitus. A Preliminary Study.

作者信息

Domínguez-Domínguez Adrián, Martínez-Guardado Ismael, Domínguez-Muñoz Francisco Javier, Barrios-Fernandez Sabina, Morenas-Martín Jesús, Garcia-Gordillo Miguel Angel, Carlos-Vivas Jorge

机构信息

Promoting a Healthy Society Research Group (PHeSO), Faculty of Sport Sciences, University of Extremadura, 10003 Cáceres, Spain.

Faculty of Life and Nature Sciences, Nebrija University, 28015 Madrid, Spain.

出版信息

J Clin Med. 2021 Dec 13;10(24):5829. doi: 10.3390/jcm10245829.

Abstract

Type 1 Diabetes Mellitus (T1D) is a chronic autoimmune disease characterized by the selective destruction of the beta cells of the pancreas causing an absolute deficiency of insulin for life. This pathology carries associated risks so that it is essential to measure Health-Related Quality of Life (HRQoL) in this population. The aim was to analyse associations between the level of physical activity and HRQoL in people with T1D. The sample consisted of 172 participants with T1D diagnoses, between 18 and 49 years (31.29 ± 8.17). The participants answered different questionnaires related to physical activity (IPAQ) and HRQoL (EsDQOL, ViDa1, 15D, and EQ-5D-5L). The results showed significant correlations between the level of physical activity and HRQoL. Vigorous physical activity had an impact on the HRQoL questionnaires, such as the well-being dimension (rho = 0.349; < 0.001) of the ViDa1 questionnaire. A significant correlation between total physical activity and levels of anxiety and depression was observed: anxiety (15D) (rho = 0.328; < 0.001) and anxiety/depression (EQ-5D-5L) (rho = 0.324; < 0.001). The present study showed associations between higher levels of physical activity and higher HRQoL parameters in the population with T1D, which can be erected as a reason for exercise prescription in these patients.

摘要

1型糖尿病(T1D)是一种慢性自身免疫性疾病,其特征是胰腺β细胞被选择性破坏,导致终生绝对缺乏胰岛素。这种病理状况存在相关风险,因此在该人群中测量健康相关生活质量(HRQoL)至关重要。目的是分析1型糖尿病患者身体活动水平与健康相关生活质量之间的关联。样本包括172名诊断为1型糖尿病的参与者,年龄在18至49岁之间(31.29±8.17)。参与者回答了与身体活动(IPAQ)和健康相关生活质量(EsDQOL、ViDa1、15D和EQ-5D-5L)相关的不同问卷。结果显示身体活动水平与健康相关生活质量之间存在显著相关性。剧烈身体活动对健康相关生活质量问卷有影响,如ViDa1问卷的幸福感维度(rho = 0.349;<0.001)。观察到总体身体活动与焦虑和抑郁水平之间存在显著相关性:焦虑(15D)(rho = 0.328;<0.001)和焦虑/抑郁(EQ-5D-5L)(rho = 0.324;<0.001)。本研究表明,1型糖尿病患者中较高水平的身体活动与较高的健康相关生活质量参数之间存在关联,这可作为为这些患者开具运动处方的一个理由。

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