Makalanda Levansri, Lansley Joseph, Wong Ken, Spooner Oliver, Bhogal Pervinder
Department of Interventional Neuroradiology, The Royal London Hospital, Whitechapel Road, London E1 1BB, UK.
Department of Stroke, The Royal London Hospital, Whitechapel Road, London E1 1BB, UK.
J Clin Med. 2021 Dec 13;10(24):5844. doi: 10.3390/jcm10245844.
Aspiration thrombectomy is a widely accepted treatment option for large vessel occlusion (LVO). The MIVI aspiration system has a novel design to maximize the lumen size. We present the results of our initial experience with this innovative aspiration thrombectomy system.
Retrospectively, we reviewed our database to find all cases of LVO treated with the MIVI Q system (February 2019 and July 2020). In addition, we recorded the baseline demographics, NIHSS, ASPECT, mTICI scores, procedural time, complications, and 90 day mRS.
Herein, we identified 25 patients with an average age of 65.3 ± 19.3 years (range 19-89), majority of whom were female ( = 14, 56%). The average NIHSS was 16.9 ± 6.7 (range 6-30), and the average CT ASPECT was 7.9 ± 1.4 (range 5-10). The most common clot location was the M1 segment of the MCA ( = 16, 64%). Four of the patients had tandem lesions (16%). The average clot length was 21.7 ± 31 mm (range 2-130 mm). Of the 23 cases where the Q catheter reached the proximal clot face, mTICI ≥ 2b was achieved on the first pass in 11 cases (44%), and at the end of the 'Q aspiration' only the procedures with 16 patients achieved mTICI ≥ 2b recanalization (64%). Stent-retrievers were used in 13 cases (52%). At the end of the procedure, 24 patients (96%) achieved mTICI ≥ 2b with 18 patients (72%) achieving mTICI ≥ 2c. The average number of passes with the Q catheter, including when it was used for SOLUMBRA, was 2.1 ± 2.2 (range 1-10). The mean procedure time was 69 ± 32 mins (range 7-116 mins). No complications were associated with the MIVI Q.
The MIVI aspiration system is a novel technology with regards to aspiration mechanical thrombectomy. The system is easy to use with early results comparable to other large-bore catheter systems. However, further studies are needed.
抽吸血栓切除术是治疗大血管闭塞(LVO)广泛接受的治疗选择。MIVI抽吸系统具有新颖的设计,可最大程度地扩大管腔尺寸。我们展示了使用这种创新抽吸血栓切除术系统的初步经验结果。
我们回顾性地查阅数据库,以查找所有使用MIVI Q系统治疗的LVO病例(2019年2月至2020年7月)。此外,我们记录了基线人口统计学、美国国立卫生研究院卒中量表(NIHSS)、脑梗死溶栓治疗的脑动脉侧支循环分级(ASPECT)、脑梗死溶栓分级(mTICI)评分、手术时间、并发症以及90天改良Rankin量表(mRS)评分。
在此,我们确定了25例患者,平均年龄为65.3±19.3岁(范围19 - 89岁),其中大多数为女性(n = 14,56%)。平均NIHSS为16.9±6.7(范围6 - 30),平均CT ASPECT为7.9±1.4(范围5 - 10)。最常见的血栓部位是大脑中动脉M1段(n = 16,64%)。4例患者有串联病变(16%)。平均血栓长度为21.7±31mm(范围2 - 130mm)。在Q导管到达近端血栓表面的23例病例中,11例(44%)首次通过时达到mTICI≥2b,仅在“Q抽吸”结束时,16例患者的手术达到mTICI≥2b再通(64%)。13例(52%)使用了支架取栓器。手术结束时,24例患者(96%)达到mTICI≥2b,18例患者(72%)达到mTICI≥2c。包括用于Solumbra技术时,Q导管的平均通过次数为2.1±2.2(范围1 - 10)。平均手术时间为69±32分钟(范围7 - 116分钟)。未发现与MIVI Q相关的并发症。
MIVI抽吸系统是一种关于抽吸机械血栓切除术的新技术。该系统易于使用,早期结果与其他大口径导管系统相当。然而,仍需要进一步研究。