Suppr超能文献

年轻竞技运动员的主动脉根部尺寸与脉搏波速度

Aortic Root Dimensions and Pulse Wave Velocity in Young Competitive Athletes.

作者信息

Engl Tobias, Müller Jan, Fisel Patrick, Oberhoffer-Fritz Renate

机构信息

Institute of Preventive Pediatrics, Technical University Munich, 80992 Munich, Germany.

Department of Pediatric Cardiology, German Heart Center Munich, 80636 Munich, Germany.

出版信息

J Clin Med. 2021 Dec 17;10(24):5922. doi: 10.3390/jcm10245922.

Abstract

The assessment of aortic root dimensions is a cornerstone in cardiac pre-participation screening as dilation can result in severe cardiac events. Moreover, it can be a hint for an underlying connective tissue disease, which needs individualized sports counseling. This study examines the prevalence of aortic root dilatation in a cohort and its relationship to arterial stiffness as an early marker of cardiovascular risk due to vascular aging. From May 2012 to March 2018, we examined 281 young male athletes (14.7 ± 2.1 years) for their aortic root dimension. Moreover, we noninvasively assessed arterial stiffness parameter during pre-participation screening. Mean aortic diameter was 25.9 ± 3.1 mm and 18 of the 281 (6.4%) athletes had aortic root dilation without other clinical evidence of connective tissue disease. After adjusting for BSA, there was no association of aortic root diameter to pulse wave velocity ( = -0.054 = 0.368) nor to central blood pressure ( = -0.029 = 0.634). Thus, although a significant proportion of young athletes had aortic root dilatation, which certainly needs regular follow up, no correlation with arterial stiffness was found. It could be suggested that a dilated aortic root in young athletes does not alter pulse waveform and pulse reflection, and thus there is no increased cardiovascular risk in those subjects.

摘要

主动脉根部尺寸的评估是心脏参与运动前筛查的基石,因为主动脉扩张可能导致严重的心脏事件。此外,它可能提示存在潜在的结缔组织疾病,这需要个性化的运动咨询。本研究调查了一组人群中主动脉根部扩张的患病率及其与动脉僵硬度的关系,动脉僵硬度是血管老化导致心血管风险的早期标志物。2012年5月至2018年3月,我们对281名年轻男性运动员(14.7±2.1岁)的主动脉根部尺寸进行了检查。此外,我们在参与运动前筛查期间对动脉僵硬度参数进行了无创评估。平均主动脉直径为25.9±3.1mm,281名运动员中有18名(6.4%)存在主动脉根部扩张,但无其他结缔组织疾病的临床证据。在调整体表面积后,主动脉根部直径与脉搏波速度(r=-0.054,P=0.368)和中心血压(r=-0.029,P=0.634)均无关联。因此,尽管相当一部分年轻运动员存在主动脉根部扩张,这当然需要定期随访,但未发现与动脉僵硬度相关。可以认为,年轻运动员的主动脉根部扩张不会改变脉搏波形和脉搏反射,因此这些受试者的心血管风险不会增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee80/8708780/c22b6f563dc8/jcm-10-05922-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验