Davidescu Eugenia Irene, Odajiu Irina, Tulbă Delia, Cucu Camelia, Popescu Bogdan Ovidiu
Department of Clinical Neurosciences, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Neurology, Colentina Clinical Hospital, 020125 Bucharest, Romania.
J Clin Med. 2021 Dec 17;10(24):5932. doi: 10.3390/jcm10245932.
Multiple sclerosis (MS) patients tend to present peculiar personality traits that highly impact their quality of life. Our study aimed to determine which personality traits are more common in MS patients compared to a sex- and age-matched control group.
Patients with relapsing-remitting MS along with a sex- and age-matched control group were included. All subjects completed the DECAS Personality Inventory and an additional form including demographic characteristics. Data (including descriptive statistics and univariate and multivariate analysis) were analyzed using SPSS.
122 subjects were included, out of which 61 were in the patient group, mostly females (71.31%) with a mean age of 42.06 ± 10.46 years. Mean duration of disease was 10.18 ± 5.53 years and mean EDSS score was 2.09; 36% of patients were treated with Interferon-beta 1a. Subjects in the patient group presented significantly lower scores for extraversion ( = 0.036), specifically those with higher EDSS score, even after adjusting for possible confounders (age, sex, marital status, early retirement, alcohol, and tobacco consumption). Additionally, regarding orientation in life, MS patients were more often philosophers ( = 0.001), especially young males, whereas the dominant emotional feeling was less common, the actor profile ( = 0.022). Regarding task involvement, MS patients were often passive and compassionate concerning other people. Higher EDSS score also correlated with avoidant ( = 0.006) and melancholic ( = 0.043) personality traits. Subjects with higher education associated more often pragmatic, experimenter, popular, and optimist traits, whereas the elderly had actor, authoritarian, and experimenter profiles.
Some MS patients may have reduced levels of extraversion and specific personality traits compared to age- and sex-matched subjects. Determining the exact personality profile might help the neurologist to establish a better therapeutic alliance and to apply specific interventions.
多发性硬化症（MS）患者往往表现出独特的人格特质，这对他们的生活质量有很大影响。我们的研究旨在确定与性别和年龄匹配的对照组相比，哪些人格特质在MS患者中更常见。
纳入复发缓解型MS患者以及性别和年龄匹配的对照组。所有受试者均完成了DECAS人格量表和一份包含人口统计学特征的附加表格。使用SPSS对数据（包括描述性统计以及单变量和多变量分析）进行分析。
共纳入122名受试者，其中患者组61人，大多为女性（71.31%），平均年龄为42.06±10.46岁。疾病平均病程为10.18±5.53年，平均扩展残疾状态量表（EDSS）评分为2.09；36%的患者接受了干扰素-β1a治疗。患者组受试者的外向性得分显著较低（P = 0.036），尤其是那些EDSS评分较高的患者，即使在调整了可能的混杂因素（年龄、性别、婚姻状况、提前退休、饮酒和吸烟）之后也是如此。此外，在生活取向方面，MS患者更常是哲学家（P = 0.001），尤其是年轻男性，而主导情感类型较不常见，即演员型（P = 0.022）。在任务参与方面，MS患者往往对他人被动且富有同情心。较高的EDSS评分还与回避型（P = 0.006）和抑郁型（P = 0.043）人格特质相关。受过高等教育的受试者更常具有务实、实验者、受欢迎和乐观的特质，而老年人则具有演员、权威和实验者型人格。
与年龄和性别匹配的受试者相比，一些MS患者的外向性水平和特定人格特质可能有所降低。确定确切的人格特征可能有助于神经科医生建立更好的治疗联盟并应用特定干预措施。
