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多发性硬化症：诊断、管理及未来机遇

Multiple Sclerosis: Diagnosis, Management, and Future Opportunities.

作者信息

Maida Elisabetta, Lavorgna Luigi

机构信息

Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, 80131 Napoli, Italy.

出版信息

J Clin Med. 2023 Jul 8;12(14):4558. doi: 10.3390/jcm12144558.

DOI:10.3390/jcm12144558
PMID:37510673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10380519/
Abstract

Multiple sclerosis (MS) is one of the most common inflammatory neurological diseases which leads to a highly heterogeneous set of symptoms and signs due to the differential involvement of the motor, sensory, visual, and autonomic systems [...].

摘要

多发性硬化症（MS）是最常见的炎症性神经疾病之一，由于运动、感觉、视觉和自主神经系统的不同程度受累，会导致一系列高度异质性的症状和体征[……]

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本文引用的文献

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Health related quality of life in the domain of physical activity predicts confirmed disability progression in people with relapsing remitting multiple sclerosis.体力活动领域的健康相关生活质量可预测复发缓解型多发性硬化患者的确诊残疾进展。
Mult Scler Relat Disord. 2023 Jul;75:104731. doi: 10.1016/j.msard.2023.104731. Epub 2023 Apr 28.
2
Disease Reactivation in Secondary Progressive Multiple Sclerosis Patients Switching from Fingolimod to Siponimod: A Case Series.从芬戈莫德转换为西波尼莫德的继发进展型多发性硬化症患者的疾病再激活：病例系列
J Clin Med. 2022 Oct 13;11(20):6033. doi: 10.3390/jcm11206033.
3
Quality of Life Changes in Early-Onset Multiple Sclerosis: A 4-Year Follow-Up Study.早发性多发性硬化症患者生活质量的变化：一项4年随访研究
J Clin Med. 2022 Sep 4;11(17):5226. doi: 10.3390/jcm11175226.
4
Symptom-Level Disability Status Assessed with an Electronic Unsupervised Patient-Reported Expanded Disability Status Scale (ePR-EDSS) in Multiple Sclerosis Patients-The Example of Croatia.采用电子无监督患者报告扩展残疾状态量表（ePR-EDSS）评估多发性硬化症患者的症状水平残疾状况——以克罗地亚为例。
J Clin Med. 2022 Jul 14;11(14):4081. doi: 10.3390/jcm11144081.
5
Cutaneous Adverse Reactions Associated with Monoclonal Antibodies Treatment in Multiple Sclerosis: Case Reports and Short Literature Review.多发性硬化症中与单克隆抗体治疗相关的皮肤不良反应：病例报告及文献综述
J Clin Med. 2022 Jun 27;11(13):3702. doi: 10.3390/jcm11133702.
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Effect of Rituximab Compared with Natalizumab and Fingolimod in Patients with Relapsing-Remitting Multiple Sclerosis: A Cohort Study.利妥昔单抗与那他珠单抗和芬戈莫德治疗复发缓解型多发性硬化症患者的疗效比较：一项队列研究
J Clin Med. 2022 Jun 22;11(13):3584. doi: 10.3390/jcm11133584.
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PECAM-1 Is Down-Regulated in γδT Cells during Remission, but Up-Regulated in Relapse of Multiple Sclerosis.血小板内皮细胞黏附分子-1（PECAM-1）在缓解期的γδT细胞中表达下调，但在多发性硬化症复发期上调。
J Clin Med. 2022 Jun 4;11(11):3210. doi: 10.3390/jcm11113210.
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J Clin Med. 2022 Apr 7;11(8):2081. doi: 10.3390/jcm11082081.
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J Clin Med. 2022 Jan 23;11(3):567. doi: 10.3390/jcm11030567.