Manole Simona, Budurea Claudia, Pop Sorin, Iliescu Alin M, Ciortea Cristiana A, Iancu Stefania D, Popa Loredana, Coman Mihaela, Szabó László, Coman Vasile, Bálint Zoltán
IMOGEN Research Institute, County Clinical Emergency Hospital, 400006 Cluj-Napoca, Romania.
Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Life (Basel). 2021 Dec 8;11(12):1362. doi: 10.3390/life11121362.
We aimed to compare cardiac volumes measured with echocardiography (echo) and cardiac magnetic resonance imaging (MRI) in a mixed cohort of healthy controls (controls) and patients with atrial fibrillation (AF).
In total, 123 subjects were included in our study; 99 full datasets were analyzed. All the participants underwent clinical evaluation, EKG, echo, and cardiac MRI acquisition. Participants with full clinical data were grouped into 63 AF patients and 36 controls for calculation of left atrial volume (LA Vol) and 51 AF patients and 30 controls for calculation of left ventricular end-diastolic volume (LV EDV), end-systolic volume (ESV), and LV ejection fraction (LV EF).
No significant differences in LA Vol were observed ( > 0.05) when measured by either echo or MRI. However, echo provided significantly lower values for left ventricular volume ( < 0.0001). The echo LA Vol of all the subjects correlated well with that measured by MRI (Spearmen correlation coefficient r = 0.83, < 0.0001). When comparing the two methods, significant positive correlations of EDV (all subjects: r = 0.55; Controls: r = 0.71; and AF patients: r = 0.51) and ESV (all subjects: r = 0.62; Controls: r = 0.47; and AF patients: r = 0.66) were found, with a negative bias for values determined using echo. For a subgroup of participants with ventricular volumes smaller than 49.50 mL, this bias was missing, thus in this case echocardiography could be used as an alternative for MRI.
Good correlation and reduced bias were observed for LA Vol and EF determined by echo as compared to cardiac MRI in a mixed cohort of patients with AF and healthy volunteers. For the determination of volume values below 49.50 mL, an excellent correlation was observed between values obtained using echo and MRI, with comparatively reduced bias for the volumes determined by echo. Therefore, in certain cases, echocardiography could be used as a less expensive, less time-consuming, and contraindication free alternative to MRI for cardiac volume determination.
我们旨在比较在健康对照者（对照组）和心房颤动（AF）患者的混合队列中，通过超声心动图（echo）和心脏磁共振成像（MRI）测量的心脏容积。
我们的研究共纳入123名受试者；分析了99份完整数据集。所有参与者均接受了临床评估、心电图、echo和心脏MRI检查。具有完整临床数据的参与者被分为63名AF患者和36名对照组，用于计算左心房容积（LA Vol）；51名AF患者和30名对照组用于计算左心室舒张末期容积（LV EDV）、收缩末期容积（ESV）和左心室射血分数（LV EF）。
通过echo或MRI测量时，LA Vol未观察到显著差异（>0.05）。然而，echo测得的左心室容积显著更低（<0.0001）。所有受试者的echo LA Vol与MRI测得的结果相关性良好（斯皮尔曼相关系数r = 0.83，<0.0001）。比较两种方法时，发现EDV（所有受试者：r = 0.55；对照组：r = 0.71；AF患者：r = 0.51）和ESV（所有受试者：r = 0.62；对照组：r = 0.47；AF患者：r = 0.66）存在显著正相关，且echo测得的值存在负偏差。对于心室容积小于49.50 mL的参与者亚组，这种偏差不存在，因此在这种情况下，超声心动图可作为MRI的替代方法。
在AF患者和健康志愿者的混合队列中，与心脏MRI相比，echo测定的LA Vol和EF具有良好的相关性且偏差减小。对于低于49.50 mL的容积值测定，echo和MRI获得的值之间观察到极好的相关性，echo测定的容积偏差相对减小。因此，在某些情况下，超声心动图可作为一种成本更低、耗时更少且无禁忌证的替代方法，用于心脏容积测定，以替代MRI。
