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基于健康信念模型的动机性访谈对肺结核患者药物依从性和治疗成功的影响。

A Health Belief Model-Based Motivational Interviewing for Medication Adherence and Treatment Success in Pulmonary Tuberculosis Patients.

机构信息

Doctoral Study Program, Medical Faculty, Udayana University, Denpasar 80361, Indonesia.

Department of Internal Medicine, Medical Faculty, Udayana University, Denpasar 80234, Indonesia.

出版信息

Int J Environ Res Public Health. 2021 Dec 15;18(24):13238. doi: 10.3390/ijerph182413238.

Abstract

Medication adherence behavior plays a central role in the success of tuberculosis (TB) treatment. Conventional motivation is not optimal in strengthening long-term medication adherence. A motivational interviewing (MI) communication motivation model based on the Health Belief Model (HBM) was designed with the main objective of improving medication adherence and treatment success. This study used an experimental design with a randomized posttest-only control group design. The intervention and control groups consisted of 107 TB patients each, who were selected by random cluster sampling. The study was conducted from November 2020 to June 2021 at 38 public health centers in Bali Province. The HBM-based MI model intervention was given in seven counseling sessions, pill count percentages were used to measure medication adherence, and treatment success was based on sputum examination results. Logistic regression was used to assess the effect of the intervention on medication adherence and treatment success. Logistic regression analysis showed that MI-based HBM and knowledge were the most influential variables for increasing medication adherence and treatment success. Medication adherence was 4.5 times greater (ARR = 4.51, = 0.018) and treatment success was 3.8 times greater (ARR = 3.81, < 0.038) in the intervention group compared to the control group, while the secondary outcome of knowledge of other factors together influenced medication adherence and treatment success. The conclusion is that the HBM-based MI communication motivation model creates a patient-centered relationship by overcoming the triggers of treatment barriers originating from the HBM construct, effectively increasing medication adherence and treatment success for TB patients, and it needs further development by involving families in counseling for consistent self-efficacy of patients in long-term treatment.

摘要

药物依从行为在结核病(TB)治疗的成功中起着核心作用。传统的激励方法在加强长期药物依从性方面并不理想。本研究旨在设计一种基于健康信念模型(HBM)的动机性访谈(MI)沟通动机模型,以提高药物依从性和治疗成功率。该研究采用实验设计,随机后测试仅控制组设计。干预组和对照组各有 107 例结核病患者,采用随机整群抽样法选取。研究于 2020 年 11 月至 2021 年 6 月在巴厘省 38 个公共卫生中心进行。在七次咨询中实施基于 HBM 的 MI 模型干预,使用药物计数百分比来衡量药物依从性,根据痰检结果判断治疗成功率。采用逻辑回归评估干预对药物依从性和治疗成功率的影响。逻辑回归分析显示,基于 HBM 的 MI 和知识是影响药物依从性和治疗成功率的最主要变量。与对照组相比,干预组的药物依从性提高了 4.5 倍(ARR=4.51, =0.018),治疗成功率提高了 3.8 倍(ARR=3.81, <0.038),而其他因素的知识这一次要结局共同影响药物依从性和治疗成功率。结论是,基于 HBM 的 MI 沟通动机模型通过克服源自 HBM 结构的治疗障碍触发因素,创造了以患者为中心的关系,有效提高了结核病患者的药物依从性和治疗成功率,需要进一步发展,让家庭参与咨询,以保持患者在长期治疗中的自我效能感。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/855c/8701142/0808beec6381/ijerph-18-13238-g001.jpg

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