核医学患者暴露于电离辐射与外周血T淋巴细胞中次黄嘌呤磷酸核糖转移酶（HPRT）突变频率的升高有关。 - Suppr

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超能文献

Exposure of nuclear medicine patients to ionizing radiation is associated with rises in HPRT- mutant frequency in peripheral T-lymphocytes.

作者信息

Seifert A M, Bradley W E, Messing K

出版信息

Mutat Res. 1987 May;191(1):57-63. doi: 10.1016/0165-7992(87)90171-0.

DOI:10.1016/0165-7992(87)90171-0

PMID:3494940

Abstract

摘要

相似文献

Exposure of nuclear medicine patients to ionizing radiation is associated with rises in HPRT- mutant frequency in peripheral T-lymphocytes.核医学患者暴露于电离辐射与外周血T淋巴细胞中次黄嘌呤磷酸核糖转移酶（HPRT）突变频率的升高有关。

Mutat Res. 1987 May;191(1):57-63. doi: 10.1016/0165-7992(87)90171-0.

Radiation quality affects the efficiency of induction and the molecular spectrum of HPRT mutations in human T cells.辐射质量会影响人类T细胞中次黄嘌呤磷酸核糖转移酶（HPRT）突变的诱导效率和分子谱。

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Monitoring hprt mutant frequency over time in T-lymphocytes of people accidentally exposed to high doses of ionizing radiation.监测意外暴露于高剂量电离辐射的人群T淋巴细胞中hprt突变频率随时间的变化。

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Mutant frequency of radiotherapy technicians appears to be associated with recent dose of ionizing radiation.

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Mutant frequency at the HPRT locus in peripheral blood T-lymphocytes of atomic bomb survivors.原子弹爆炸幸存者外周血T淋巴细胞中次黄嘌呤-鸟嘌呤磷酸核糖转移酶（HPRT）基因座的突变频率。

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The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.吸烟和饮食对正常人群循环T淋巴细胞中次黄嘌呤磷酸核糖基转移酶（hprt）突变频率的影响。

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Southern-blot analyses of human T-lymphocyte mutants induced in vitro by gamma-irradiation.对γ射线体外诱导的人T淋巴细胞突变体进行的Southern印迹分析。

Mutat Res. 1990 Feb;240(2):143-9. doi: 10.1016/0165-1218(90)90018-w.

HPRT-mutant frequency and lymphocyte characteristics of workers exposed to ionizing radiation on a sporadic basis: a comparison of two exposure indicators, job title and dose.偶尔暴露于电离辐射的工人的次黄嘌呤磷酸核糖转移酶（HPRT）突变频率和淋巴细胞特征：两种暴露指标（职称和剂量）的比较

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Dose-rate effect on the induction of HPRT mutants in human G0 lymphocytes exposed in vitro to gamma radiation.剂量率对体外暴露于γ辐射的人G0淋巴细胞中HPRT突变体诱导的影响。

Radiat Res. 2006 Jan;165(1):43-50. doi: 10.1667/rr-3467.1.

Studies on chromosome aberrations and HPRT mutations in lymphocytes and GPA mutation in erythrocytes of atomic bomb survivors.

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引用本文的文献

In vivo mutations in human blood cells: biomarkers for molecular epidemiology.人类血细胞中的体内突变：分子流行病学的生物标志物。

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Somatic cell gene mutations in humans: biomarkers for genotoxicity.人类体细胞基因突变：遗传毒性的生物标志物。

Environ Health Perspect. 1993 Oct;101 Suppl 3(Suppl 3):193-201. doi: 10.1289/ehp.93101s3193.

Human somatic mutation assays as biomarkers of carcinogenesis.人体体细胞突变检测作为致癌作用的生物标志物

Environ Health Perspect. 1991 Aug;94:135-41. doi: 10.1289/ehp.94-1567966.

Fine structure mapping of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene region of the human X chromosome (Xq26).人类X染色体（Xq26）次黄嘌呤-鸟嘌呤磷酸核糖转移酶（HPRT）基因区域的精细结构图谱

Am J Hum Genet. 1991 Aug;49(2):267-78.

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