Young Daisy, Kanuri Sri Harsha, Akella Krishna, Murtaza Ghulam, Gopinathannair Rakesh, Lakkireddy Dhanunjaya
Internal Medicine Resident at Stony Brook Southampton Hospital, New York.
Kansas City Heart Rhythm Institute, Overland Park, KS.
J Atr Fibrillation. 2020 Aug 31;13(2):2247. doi: 10.4022/jafib.2247. eCollection 2020 Aug.
Sarcoidosis is a complex systemic condition resulting in formation of non-caseating granulomas. Infiltrative disease in cardiac sarcoidosis can have significant ramifications on mortality and is one of the few indications for systemic immunosuppressive therapy. In the patient on immunosuppressive medication, resultant sequelae such as skin and soft tissue infections are common and must be differentiated from cutaneous forms of sarcoidosis and other skin pathologies. Patients with humoral or cellular immunodeficiencies may have cutaneous lesions secondary to endemic fungi, mycobacterium, viral diseases, parasites, or encapsulated organisms. We report a rare case of cardiac sarcoidosis on immunosuppressive therapy, with a series of cutaneous sequelae due to opportunistic infection.
结节病是一种导致非干酪样肉芽肿形成的复杂全身性疾病。心脏结节病的浸润性疾病可对死亡率产生重大影响,是全身免疫抑制治疗的少数适应症之一。在接受免疫抑制药物治疗的患者中,诸如皮肤和软组织感染等后遗症很常见,必须与结节病的皮肤形式和其他皮肤病变相鉴别。体液或细胞免疫缺陷的患者可能有继发于地方性真菌、分枝杆菌、病毒疾病、寄生虫或包膜生物的皮肤病变。我们报告一例接受免疫抑制治疗的心脏结节病罕见病例,该病例因机会性感染出现了一系列皮肤后遗症。