Kumar H K Sharath, M N Gayathri, M Bharathi, T Ravikumar
Associate Professor, Department of Pathology.
J Clin Diagn Res. 2013 Aug;7(8):1725-6. doi: 10.7860/JCDR/2013/6108.3303. Epub 2013 Aug 1.
Cutaneous lesions are a part of common manifestation in multi-systemic sarcoidosis and skin involvement occurs in 20% to 35% of the patients with systemic disease. An exclusive cutaneous involvement is rare and it is reported in about 4%-5% of the patients of sarcoidosis. These lesions have been classified into specific and non-specific, depending on the presence of non- caseating granulomas, on histopathologic studies. In the present study, we are reporting two cases of isolated cutaneous sarcoidosis without systemic manifestations, which is a rare presentation. Sarcoidosis will continue to challenge even the most experienced clinicians with respect to a high degree of suspicion and further investigations for diagnosing and treating this disorder.
皮肤病变是多系统结节病常见表现的一部分，20%至35%的系统性疾病患者会出现皮肤受累。单纯皮肤受累情况罕见，据报道在结节病患者中约占4% - 5%。根据组织病理学研究中是否存在非干酪样肉芽肿，这些病变可分为特异性和非特异性。在本研究中，我们报告了两例无全身表现的孤立性皮肤结节病病例，这是一种罕见的表现形式。对于结节病，即使是经验最丰富的临床医生，在高度怀疑以及进一步诊断和治疗该疾病的调查方面，仍将面临挑战。
