α-1-抗糜蛋白酶对通透化人细胞中DNA合成的影响。
Effect of alpha-1-antichymotrypsin on DNA synthesis in permeabilized human cells.
作者信息
Tsuda M, Umezawa Y, Masuyama M, Yamaguchi K, Katsunuma T
出版信息
Biochem Biophys Res Commun. 1987 Apr 14;144(1):409-14. doi: 10.1016/s0006-291x(87)80525-9.
PMID:3495264
Abstract
The effect of Alpha-1-antichymotrypsin(ACT) on DNA synthesis was studied using lysolecithin-permeabilized cultured human stomach carcinoma cells. ACT added in medium inhibited DNA synthesis and the degree of inhibition is incubation time dependent. It is proportional to ACT concentration and the concentration of ACT required for 50% inhibition was 0.8 mg/ml.
摘要
利用溶血卵磷脂通透处理的培养人胃癌细胞研究了α1抗糜蛋白酶（ACT）对DNA合成的影响。添加到培养基中的ACT抑制DNA合成，抑制程度与孵育时间有关。它与ACT浓度成正比，50%抑制所需的ACT浓度为0.8毫克/毫升。
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