Heinrich Marcel A, Mangia Marina, Prakash Jai
Engineered Therapeutics Section, Department of Advanced Organ Bioengineering and Therapeutics, Technical Medical Centre, University of Twente, 7500AE Enschede, The Netherlands.
Engineered Therapeutics Section, Department of Advanced Organ Bioengineering and Therapeutics, Technical Medical Centre, University of Twente, 7500AE Enschede, The Netherlands.
Trends Biotechnol. 2022 May;40(5):532-534. doi: 10.1016/j.tibtech.2021.12.001. Epub 2021 Dec 22.
Endotoxins are commonly present in both naturally derived and synthetic biomaterials. This Forum highlights the consequences of endotoxin contamination in biomaterials on different engineered tissues, such as bone, skin, or cartilage, and discusses the potential effects on novel 3D immunocompetent pathophysiological models.
内毒素普遍存在于天然来源和合成的生物材料中。本次论坛重点介绍了生物材料中内毒素污染对不同工程组织(如骨骼、皮肤或软骨)的影响,并讨论了其对新型3D免疫活性病理生理模型的潜在影响。