Suppr超能文献

急性尿潴留的最佳非手术治疗方法:有哪些新进展?

Best nonsurgical managements of acute urinary retention: what's new?

作者信息

Baboudjian Michael, Peyronnet Benoit, Boissier Romain, Robert Grégoire, Cornu Jean-Nicolas, Misrai Vincent, Pradere Benjamin

机构信息

Department of Urology, La Conception Hospital.

Department of Urology, North Hospital, Aix-Marseille University, APHM, Marseille.

出版信息

Curr Opin Urol. 2022 Mar 1;32(2):124-130. doi: 10.1097/MOU.0000000000000969.

Abstract

PURPOSE OF REVIEW

To provide a comprehensive review of the nonsurgical management of acute urinary retention (AUR).

RECENT FINDINGS

A recent meta-analysis confirmed that α-blockers are associated with higher rates of successful trial without catheter (TWOC) compared with placebo, while combination therapies do not significantly reduce the rate of recatheterization. Compared with standard TWOC, bladder perfusion with physiological serum prior to catheter removal is a simple and cost-effective method to increase TWOC success rates (odds ratio 2.41, 95% confidence interval 1.53-3.8), and to reduce time-to-discharge (-89.68 min, 95% confidence interval -160.55, -18.88). Clean intermittent catheterization (CIC) is increasingly used for urinary retention in patients with benign prostatic hyperplasia as existing data suggest that it may decrease the risk of urinary tract infections, accelerate spontaneous voiding recovery and might be more cost-effective compared with indwelling urethral catheterization. Ongoing trials are examining whether office-placed prostate stent may be a promising solution in patients with AUR.

SUMMARY

The recent development of alternative approaches to traditional TWOC may lead to new therapies for treating patients with AUR. Further studies are needed as the level of evidence from published studies remains low.

摘要

综述目的

全面回顾急性尿潴留(AUR)的非手术治疗。

最新发现

最近的一项荟萃分析证实,与安慰剂相比,α受体阻滞剂与更高的无导尿管试验成功(TWOC)率相关,而联合治疗并未显著降低再次导尿率。与标准TWOC相比,在拔除导尿管前用生理血清进行膀胱灌注是一种简单且经济有效的方法,可提高TWOC成功率(优势比2.41,95%置信区间1.53 - 3.8),并缩短出院时间(-89.68分钟,95%置信区间-160.55,-18.88)。清洁间歇性导尿(CIC)越来越多地用于良性前列腺增生患者的尿潴留,因为现有数据表明它可能降低尿路感染风险,加速自主排尿恢复,并且与留置尿道导尿相比可能更具成本效益。正在进行的试验正在研究门诊放置前列腺支架是否可能是AUR患者的一种有前景的解决方案。

总结

传统TWOC替代方法的最新进展可能会带来治疗AUR患者的新疗法。由于已发表研究的证据水平仍然较低,因此需要进一步研究。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验