Wittebol-Post D, van Bijsterveld O P, Delleman J W
Ophthalmologica. 1987;194(1):44-9. doi: 10.1159/000309733.
Corneal thickness in the affected members of 3 families with Meesmann's epithelial dystrophy was statistically significantly less than that of the nonaffected members and of their controls. From our data one could speculate that the stroma rather than the epithelium is the primary source of the dystrophy. The thinner the cornea, the more marked the expression of the epitheliopathy. The affected members of the 2 families that were large enough for a separate analysis showed a marked difference in expressivity of the epithelial disorder. In one family the epitheliopathy showed a stationary character, while in the other there was a progression in the density of the epithelial vesicles.
在3个患有米斯曼上皮营养不良症家族的患病成员中，角膜厚度在统计学上显著低于未患病成员及其对照。根据我们的数据可以推测，营养不良的主要来源是基质而非上皮。角膜越薄，上皮病变的表现越明显。两个规模足够大、可单独分析的家族中的患病成员，上皮疾病的表达性存在显著差异。在一个家族中，上皮病变表现为静止性，而在另一个家族中，上皮小泡的密度则有进展。
