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Utilization patterns, outcomes and costs of a simplified acute malnutrition treatment programme in Burkina Faso.简化急性营养不良治疗方案在布基纳法索的利用模式、结果和成本。
Matern Child Nutr. 2022 Apr;18(2):e13291. doi: 10.1111/mcn.13291. Epub 2021 Dec 26.
2
Incidence of relapse following a new approach to simplifying and optimising acute malnutrition treatment in children aged 6-59 months: a prospective cohort in rural Northern Burkina Faso.6-59 月龄儿童简化和优化急性营养不良治疗新方法后复发的发生率:布基纳法索北部农村地区的一项前瞻性队列研究。
J Nutr Sci. 2021 Apr 19;10:e27. doi: 10.1017/jns.2021.18. eCollection 2021.
3
Simplifying and optimising the management of uncomplicated acute malnutrition in children aged 6-59 months in the Democratic Republic of the Congo (OptiMA-DRC): a non-inferiority, randomised controlled trial.简化和优化刚果民主共和国 6-59 月龄儿童单纯性急性营养不良管理:一项非劣效性、随机对照试验。
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Impact of reduced dose of ready-to-use therapeutic foods in children with uncomplicated severe acute malnutrition: A randomised non-inferiority trial in Burkina Faso.简化重度急性营养不良儿童即用型治疗食品低剂量的影响:布基纳法索一项随机非劣效性试验。
PLoS Med. 2019 Aug 27;16(8):e1002887. doi: 10.1371/journal.pmed.1002887. eCollection 2019 Aug.
5
New approach to simplifying and optimising acute malnutrition treatment in children aged 6-59 months: the OptiMA single-arm proof-of-concept trial in Burkina Faso.简化和优化 6-59 月龄儿童急性营养不良治疗的新方法:布基纳法索 OptiMA 单臂概念验证试验。
Br J Nutr. 2020 Apr 14;123(7):756-767. doi: 10.1017/S0007114519003258. Epub 2019 Dec 10.
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Availability, use, and consumption practices of ready-to-use therapeutic foods prescribed to children with uncomplicated severe acute malnutrition aged 6-59 months during outpatient treatment in Burkina Faso.布基纳法索门诊治疗 6-59 月龄无并发症严重急性营养不良儿童时,即食治疗食品的供应、使用和消费情况。
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8
Economic evaluation of a reduced dosage of ready-to-use therapeutic foods to treat uncomplicated severe acute malnourished children aged 6-59 months in Burkina Faso.布基纳法索减少即用型治疗性食品剂量治疗6至59个月单纯性重度急性营养不良儿童的经济学评估。
Matern Child Nutr. 2021 Jul;17(3):e13118. doi: 10.1111/mcn.13118. Epub 2021 Feb 23.
9
Optimising the dosage of ready-to-use therapeutic food in children with uncomplicated severe acute malnutrition in the Democratic Republic of the Congo: a non-inferiority, randomised controlled trial.优化刚果民主共和国单纯性重度急性营养不良儿童即食治疗性食品的剂量:一项非劣效性随机对照试验。
EClinicalMedicine. 2023 Feb 28;58:101878. doi: 10.1016/j.eclinm.2023.101878. eCollection 2023 Apr.
10
Effectiveness of acute malnutrition treatment with a simplified, combined protocol in Central African Republic: An observational cohort study.简化联合方案治疗中非共和国急性营养不良的效果:一项观察性队列研究。
Matern Child Nutr. 2024 Oct;20(4):e13691. doi: 10.1111/mcn.13691. Epub 2024 Jul 2.

引用本文的文献

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Am J Trop Med Hyg. 2023 Jun 12;109(2):460-465. doi: 10.4269/ajtmh.22-0714. Print 2023 Aug 2.

本文引用的文献

1
Improving estimates of the burden of severe wasting: analysis of secondary prevalence and incidence data from 352 sites.改善严重消瘦负担的估计:来自 352 个地点的二级患病率和发病率数据的分析。
BMJ Glob Health. 2021 Mar;6(3). doi: 10.1136/bmjgh-2020-004342.
2
[Effectiveness and cost of management of severe acute malnutrition with complications in Kaya, Burkina Faso].[布基纳法索卡亚地区重度急性营养不良伴并发症的管理效果与成本]
Pan Afr Med J. 2019 Nov 14;34:145. doi: 10.11604/pamj.2019.34.145.17946. eCollection 2019.
3
New approach to simplifying and optimising acute malnutrition treatment in children aged 6-59 months: the OptiMA single-arm proof-of-concept trial in Burkina Faso.简化和优化 6-59 月龄儿童急性营养不良治疗的新方法:布基纳法索 OptiMA 单臂概念验证试验。
Br J Nutr. 2020 Apr 14;123(7):756-767. doi: 10.1017/S0007114519003258. Epub 2019 Dec 10.
4
The Problem of Hospital Malnutrition in the African Continent.非洲大陆的医院营养不良问题。
Nutrients. 2019 Aug 30;11(9):2028. doi: 10.3390/nu11092028.
5
Cost-effectiveness of community-based screening and treatment of moderate acute malnutrition in Mali.马里基于社区的中度急性营养不良筛查与治疗的成本效益
BMJ Glob Health. 2019 Apr 28;4(2):e001227. doi: 10.1136/bmjgh-2018-001227. eCollection 2019.
6
MUAC as the sole discharge criterion from community-based management of severe acute malnutrition in Burkina Faso.以 MUAC 作为唯一的出院标准在布基纳法索实施严重急性营养不良的社区管理。
Matern Child Nutr. 2019 Apr;15(2):e12688. doi: 10.1111/mcn.12688. Epub 2018 Oct 10.
7
Costing of three feeding regimens for home-based management of children with uncomplicated severe acute malnutrition from a randomised trial in India.印度一项随机试验中针对无并发症重度急性营养不良儿童居家管理的三种喂养方案的成本核算
BMJ Glob Health. 2018 Mar 6;3(2):e000702. doi: 10.1136/bmjgh-2017-000702. eCollection 2018.

简化急性营养不良治疗方案在布基纳法索的利用模式、结果和成本。

Utilization patterns, outcomes and costs of a simplified acute malnutrition treatment programme in Burkina Faso.

机构信息

Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.

Inserm, French National Research Institute for Sustainable Development (IRD), Bordeaux Population Health Research Center, University of Bordeaux, Bordeaux, France.

出版信息

Matern Child Nutr. 2022 Apr;18(2):e13291. doi: 10.1111/mcn.13291. Epub 2021 Dec 26.

DOI:10.1111/mcn.13291
PMID:34957682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8932691/
Abstract

Access to treatment for acute malnutrition remains a challenge, in part due to the fragmentation of treatment programmes based on case severity. This paper evaluates utilization patterns, outcomes and associated costs for treating acute malnutrition cases among a cohort of children in Burkina Faso. This study is a secondary analysis of a proof-of-concept trial, called Optimizing treatment for acute Malnutrition (OptiMA), conducted in Burkina Faso in 2016. A total of 4958 eligible children whose mid-upper arm circumference (MUAC) was less than 125 mm or with oedema were followed weekly and given ready-to-use therapeutic foods (RUTF). We evaluated the service utilization and outcomes among patients and estimated resource use and variable cost per patient, and examined factors driving variation in resource use. Children with lower initial MUAC level grew faster but required more time to recover than those with higher initial MUAC level. They also had higher rates of death, default and nonresponse. The simplified OptiMA approach for treating acute malnutrition achieved high rates of recovery overall (84%), especially among less severe cases, with modest quantities of RUTF. The average overall variable cost per child admitted was US$38.0 (SD: 20.5) half of which was accounted for by the cost of RUTF. Cost per recovered case was correlated with case severity, ranging from US$35.1 to US$132.8. If simplified integrated programmes using severity-based RUTF dosing can increase access to treatment at earlier, less severe stages of acute malnutrition, they can help avoid more serious and costlier cases.

摘要

获得急性营养不良治疗仍然是一个挑战,部分原因是基于病情严重程度的治疗方案碎片化。本文评估了布基纳法索一个队列中急性营养不良病例的治疗利用模式、结果和相关成本。本研究是一项名为优化急性营养不良治疗(OptiMA)的概念验证试验的二次分析,该试验于 2016 年在布基纳法索进行。共有 4958 名符合条件的儿童入选,其上臂中部周长(MUAC)小于 125mm 或有水肿,每周随访一次,并给予即食治疗食品(RUTF)。我们评估了患者的服务利用情况和结局,并估计了每个患者的资源使用和可变成本,同时检查了资源使用变化的驱动因素。初始 MUAC 水平较低的儿童生长较快,但恢复时间比初始 MUAC 水平较高的儿童长。他们的死亡率、失访率和无应答率也较高。简化的 OptiMA 治疗急性营养不良的方法总体上实现了较高的恢复率(84%),尤其是在病情较轻的病例中,仅使用了少量的 RUTF。每个入院儿童的总可变平均成本为 38.0 美元(SD:20.5),其中一半由 RUTF 的成本构成。每例康复病例的成本与病情严重程度相关,范围为 35.1 美元至 132.8 美元。如果使用基于严重程度的 RUTF 剂量的简化综合方案能够在急性营养不良的早期、较轻阶段增加治疗机会,那么它们可以帮助避免更严重和更昂贵的病例。