Unit of Cardiology and Intensive Coronary Care, "Umberto I" Hospital, 84014 Nocera Inferiore (SA), Italy.
Public Health Department, University of Naples Federico II, 80131 Naples, Italy.
Rev Cardiovasc Med. 2021 Dec 22;22(4):1197-1204. doi: 10.31083/j.rcm2204128.
Atrial fibrillation (AF) can lead to embolic stroke and in subjects with non-valvular AF most of thrombi are sited in the left atrial appendage (LAA). LAA is a structure located in the free wall of heart with a wide variable and complex anatomy. LAA occlusion (LAAO) could be taken in consideration in subjects with non-valvular AF and who cannot have long-term anticoagulant therapy. It is a complex preventive procedure given the high variability of patients characteristics and several LAAO devices available nowadays. Moreover, the ideal postprocedural antithrombotic strategy is still unclear. In this review we aim to describe clinical features of patients committed for LAA occlusion and the function of multimodality imaging in subjects selection, procedural management and follow up.
心房颤动（AF）可导致栓塞性卒中，在非瓣膜性 AF 患者中，大多数血栓位于左心耳（LAA）。LAA 是位于心脏游离壁的结构，具有广泛变化且复杂的解剖结构。对于不能进行长期抗凝治疗的非瓣膜性 AF 患者，可考虑进行 LAA 闭塞（LAAO）。鉴于患者特征的高度变异性和目前可用的几种 LAAO 设备，该操作是一种复杂的预防程序。此外，理想的术后抗血栓形成策略仍不清楚。在这篇综述中，我们旨在描述接受 LAA 闭塞治疗的患者的临床特征，以及多模态成像在患者选择、手术管理和随访中的作用。
