Traditional and Complementary Medicine Practice Center, Gulhane Education and Research Hospital, University of Health Sciences, Ankara, Turkey.
Department of Sports Medicine, Gulhane Medical Faculty, University of Health Sciences, Ankara, Turkey.
J Back Musculoskelet Rehabil. 2022;35(4):763-770. doi: 10.3233/BMR-191745.
Prolotherapy (PrT) is an increasingly popular regenerative injection treatment for the management of musculoskeletal injuries. The diagnostic injection is a method for selecting suitable patients to apply PrT using subcutaneous 5% dextrose solution.
The study aims to assess the PrT usage and modifications in the treatment of chronic low back pain and lumbar disc herniation and to define diagnostic injection procedure for PrT.
Two thousand three hundred and eighty-two patients with low back pain or lumbar disc herniation were evaluated at the Traditional and Complementary Medicine Practice Center in Ankara, Turkey. Six hundred fifty-four patients were included in the study. Diagnostic injections were performed on all patients who were thought to be eligible candidates for PrT indications. A 4-or-6 week interval was allowed between treatment sessions.
Xix hundred and fifty-four patient treatments were completed. The Visual Analogue Scale (VAS) scores decreased to 5.1 ± 1.4 while 7.2 ± 1.1 before the diagnostic injection (p< 000.1). The VAS scores decreased from 7.2 ± 1.1 before the treatment to 0.9 ± 0.9 after 52 weeks of the treatment (p< 000.1). Thirty-four patients' treatments resulted in poor clinical results (5.2%), and 620 of the patients' pain improved (94.8%).
PrT can be regarded as a safe way of providing a meaningful improvement in pain and musculoskeletal function compared to the initial status. Diagnostic injection is an easy way to eliminate patients and may become a favorite treatment modality. 5% dextrose is a more simple and painless solution for PrT and also has a high success.
增生疗法（PrT）是一种越来越流行的再生注射治疗方法，用于治疗肌肉骨骼损伤。诊断性注射是一种选择适合接受 PrT 治疗的患者的方法，使用皮下 5%葡萄糖溶液。
本研究旨在评估增生疗法在慢性下腰痛和腰椎间盘突出症治疗中的应用和改良，并确定增生疗法的诊断性注射程序。
在土耳其安卡拉的传统与补充医学实践中心，对 2382 名患有下腰痛或腰椎间盘突出症的患者进行了评估。654 名患者纳入研究。对所有被认为符合 PrT 适应证的患者进行诊断性注射。治疗间隔为 4-6 周。
完成了 554 例患者的治疗。视觉模拟评分（VAS）从治疗前的 7.2 ± 1.1 降至 5.1 ± 1.4（p<000.1）。治疗前 VAS 评分为 7.2 ± 1.1，治疗后 52 周时降至 0.9 ± 0.9（p<000.1）。34 例患者的治疗结果不佳（5.2%），620 例患者的疼痛得到改善（94.8%）。
与初始状态相比，PrT 可被视为一种安全有效的改善疼痛和肌肉骨骼功能的方法。诊断性注射是一种简单的排除患者的方法，可能成为一种受欢迎的治疗方式。5%葡萄糖是一种更简单、更无痛的 PrT 解决方案，成功率也很高。
