Luque-Agudo Verónica, Gallardo-Moreno Amparo M, González-Martín María Luisa
Department of Applied Physics, University of Extremadura, 06006 Badajoz, Spain.
Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 06006 Badajoz, Spain.
Polymers (Basel). 2021 Dec 8;13(24):4289. doi: 10.3390/polym13244289.
The study of the surface properties of materials is key in determining whether the material will be suitable for medical purposes. One of these properties is hydrophobicity, which is important when assessing its behavior against bacterial adhesion. In this work, we have studied the influence of the solvent (chloroform, acetone, and tetrahydrofuran) and the substrate (glass, PTFE, silicone, and Ti6Al4V) on which polylactic acid is deposited in solution to manufacture films by solvent-casting. Thus, it has been found that there are no significant differences in hydrophobicity and surface tension among the solvents evaluated, but there are significant differences with respect to the substrates: PLA films casted on silicone are hydrophobic, while those casted on the rest of the substrates are hydrophilic. This is related to the fact that the silicone interacts with the polymer modifying its spatial arrangement, exposing its methyl groups towards the interface with the air. In this way, it has been shown that, when manufacturing PLA films, it is important to choose the right surface on which to deposit them, depending on their desired function.
材料表面性质的研究对于确定该材料是否适用于医学目的至关重要。其中一个性质是疏水性，在评估其抗细菌粘附行为时很重要。在这项工作中，我们研究了溶剂（氯仿、丙酮和四氢呋喃）以及聚乳酸在溶液中沉积以通过溶剂浇铸制造薄膜时所使用的基材（玻璃、聚四氟乙烯、硅树脂和Ti6Al4V）的影响。因此，已发现所评估的溶剂之间在疏水性和表面张力方面没有显著差异，但在基材方面存在显著差异：浇铸在硅树脂上的聚乳酸薄膜是疏水的，而浇铸在其他基材上的则是亲水的。这与硅树脂与聚合物相互作用改变其空间排列，使其甲基朝向与空气的界面有关。通过这种方式，已表明在制造聚乳酸薄膜时，根据其所需功能选择合适的沉积表面很重要。
