Matmati Jihene, Verny Christophe, Allain Philippe
Department of Psychology, University of Angers, Pays de la Loire, France (Matmati, Allain); and Department of Neurology, University Hospital Center Angers, Pays de la Loire, France (Verny, Allain).
J Neuropsychiatry Clin Neurosci. 2022 Spring;34(2):100-112. doi: 10.1176/appi.neuropsych.21060154. Epub 2021 Dec 28.
Although apathy is commonly reported among patients with Huntington's disease (HD), this psychiatric symptom has not yet been clearly defined or extensively studied in HD. Most researchers have adopted descriptive approaches, showing that apathy is a multidimensional entity but leaving the processes underlying its different dimensions relatively unexplored.
A systematic review of the literature on apathy in HD, focusing on current approaches and measurement tools, was conducted.
Searches in PubMed and PubMed Central yielded 368 articles, 25 of which were included in the present review.
This systematic review suggests that more comprehensive research is needed to help shed light on apathy in HD, especially regarding its multidimensional aspect and underlying mechanisms.
尽管亨廷顿舞蹈症（HD）患者普遍存在冷漠症状，但这种精神症状在HD中尚未得到明确界定或广泛研究。大多数研究人员采用描述性方法，表明冷漠是一个多维度的实体，但对其不同维度背后的过程相对未作探索。
对关于HD中冷漠的文献进行系统综述，重点关注当前的方法和测量工具。
在PubMed和PubMed Central数据库中检索到368篇文章，其中25篇纳入本综述。
该系统综述表明，需要开展更全面的研究以帮助阐明HD中的冷漠现象，尤其是其多维度方面及潜在机制。
