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胰腺癌的影像组学:现状与未来。

Radiomics in pancreatic cancer for oncologist: Present and future.

机构信息

Radiation Oncology Department, Ramón y Cajal University Hospital, IRYCIS, Alcalá University, 28034 Madrid, Spain.

出版信息

Hepatobiliary Pancreat Dis Int. 2022 Aug;21(4):356-361. doi: 10.1016/j.hbpd.2021.12.006. Epub 2021 Dec 16.

Abstract

Radiomics is changing the world of medicine and more specifically the world of oncology. Early diagnosis and treatment improve the prognosis of patients with cancer. After treatment, the evaluation of the response will determine future treatments. In oncology, every change in treatment means a loss of therapeutic options and this is key in pancreatic cancer. Radiomics has been developed in oncology in the early diagnosis and differential diagnosis of benign and malignant lesions, in the evaluation of response, in the prediction of possible side effects, marking the risk of recurrence, survival and prognosis of the disease. Some studies have validated its use to differentiate normal tissues from tumor tissues with high sensitivity and specificity, and to differentiate cystic lesions and pancreatic neuroendocrine tumor grades with texture parameters. In addition, these parameters have been related to survival in patients with pancreatic cancer and to response to radiotherapy and chemotherapy. This review aimed to establish the current status of the use of radiomics in pancreatic cancer and future perspectives.

摘要

放射组学正在改变医学领域,更具体地说,是改变肿瘤学领域。早期诊断和治疗可改善癌症患者的预后。治疗后,对治疗反应的评估将决定未来的治疗方案。在肿瘤学中,每次治疗方案的改变都意味着丧失治疗选择的机会,而这在胰腺癌中尤为关键。放射组学已在肿瘤学中得到发展,可用于早期诊断和良恶性病变的鉴别诊断、评估治疗反应、预测可能的副作用、标记复发风险、预测疾病的生存和预后。一些研究已经验证了其在区分正常组织和肿瘤组织方面的高敏感性和特异性,以及在区分囊性病变和胰腺神经内分泌肿瘤分级方面的应用。此外,这些参数与胰腺癌患者的生存以及对放疗和化疗的反应相关。本综述旨在阐明放射组学在胰腺癌中的应用现状及未来展望。

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