Abramovich D R, Davidson I A, Longstaff A, Pearson C K
Eur J Obstet Gynecol Reprod Biol. 1987 May;25(1):7-14. doi: 10.1016/0028-2243(87)90086-4.
It is firmly believed that sexual differentiation of the brain is linked with external genital differentiation in timing as an in utero event in the human. An extensive search for oestrogen, androgen and progestin receptors failed to show their presence despite adequate controls in cytosols from human fetal brain of gestational ages 14-20 weeks. It is possible that the receptors are present in levels so low that they are undetectable by present-day methods. Our results would indicate that hormonally influenced in utero brain sexual differentiation is most unlikely to occur as a mid-trimester event.
人们坚信，在人类中，大脑的性别分化在时间上与外生殖器的分化相关联，是子宫内发生的一个事件。尽管对孕龄14 - 20周的人类胎儿脑溶质进行了充分对照，但广泛搜索雌激素、雄激素和孕激素受体后，未能发现它们的存在。有可能这些受体的存在水平极低，以至于用目前的方法无法检测到。我们的结果表明，受激素影响的子宫内大脑性别分化极不可能在孕中期发生。
