Pandey Rajeev Kumar, Chao Paul C-P
IEEE Trans Biomed Circuits Syst. 2022 Feb;16(1):36-51. doi: 10.1109/TBCAS.2021.3138996. Epub 2022 May 9.
An adaptive PPG (Photoplethysmography) readout system for a dual-channel OLED-OPD flexible sensor is designed and developed with motion artifact (<1Hz) and ambient lighting interference successfully compensated without any additional motion sensors. The compensation is made possible by adopting multi-feedbacks and an additional reference OPD channel to cancel effectively DC drifts. In result, the quality of measured PPG is improved to the level such that long-time, continuous quality monitoring of bio-sign such as heart rate (HR) is possible. The readout is designed with an auto-programmable band-pass trans-impedance amplifier (TIA) of a 100dbΩ gain with a continuous-type DC-current cancellation loop. The rest of the readout consists of a 0.5 Hz low-pass filter, an additional second-order band-pass filter (0.1-10Hz), a difference amplifier, a motion reference channel, an analog multiplexer, a programmable gain amplifier (PGA), a digital control and a programmable DAC-PWM based auto-intensity tuned OLED driver. The readout is fabricated in an area of 9 mm via the TSMC 180nm process. The experiment result shows that the developed OLED-OPD readout senses well as small as 1nA current, with a measured dynamic range >90dB (1nA to 100 µA) and input-referred noise of 0.26 nA/√H, with power consumption of 460µW. The DC drift is successfully reduced to 1% of its average. The accuracy for heart rate is 96%.
设计并开发了一种用于双通道OLED-OPD柔性传感器的自适应光电容积脉搏波描记法(PPG)读出系统,成功补偿了运动伪影(<1Hz)和环境光干扰,无需任何额外的运动传感器。通过采用多重反馈和一个额外的参考OPD通道来有效消除直流漂移,实现了这种补偿。结果,测量的PPG质量提高到了能够对心率(HR)等生物信号进行长时间、连续质量监测的水平。读出电路设计有一个增益为100dbΩ的自动可编程带通跨阻放大器(TIA),带有连续型直流电流消除环路。读出电路的其余部分包括一个0.5Hz低通滤波器、一个额外的二阶带通滤波器(0.1 - 10Hz)、一个差分放大器、一个运动参考通道、一个模拟多路复用器、一个可编程增益放大器(PGA)、一个数字控制器和一个基于可编程DAC-PWM的自动强度调谐OLED驱动器。该读出电路通过台积电180nm工艺制造,面积为9平方毫米。实验结果表明,所开发的OLED-OPD读出电路能够很好地检测低至1nA的电流,测量动态范围>90dB(1nA至100µA),输入参考噪声为0.26 nA/√H,功耗为460µW。直流漂移成功降低到其平均值的1%。心率测量精度为96%。