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基于深度度量学习的癫痫发作自动检测方法。

An Automatic Method for Epileptic Seizure Detection Based on Deep Metric Learning.

出版信息

IEEE J Biomed Health Inform. 2022 May;26(5):2147-2157. doi: 10.1109/JBHI.2021.3138852. Epub 2022 May 5.

DOI:10.1109/JBHI.2021.3138852
PMID:34962890
Abstract

Electroencephalography (EEG) is a commonly used clinical approach for the diagnosis of epilepsy which is a life-threatening neurological disorder. Many algorithms have been proposed for the automatic detection of epileptic seizures using traditional machine learning and deep learning. Although deep learning methods have achieved great success in many fields, their performance in EEG analysis and classification is still limited mainly due to the relatively small sizes of available datasets. In this paper, we propose an automatic method for the detection of epileptic seizures based on deep metric learning which is a novel strategy tackling the few-shot problem by mitigating the demand for massive data. First, two one-dimensional convolutional embedding modules are proposed as a deep feature extractor, for single-channel and multichannel EEG signals respectively. Then, a deep metric learning model is detailed along with a stage-wise training strategy. Experiments are conducted on the publicly-available Bonn University dataset which is a benchmark dataset, and the CHB-MIT dataset which is larger and more realistic. Impressive averaged accuracy of 98.60% and specificity of 100% are achieved on the most difficult classification of interictal (subset D) vs ictal (subset E) of the Bonn dataset. On the CHB-MIT dataset, an averaged accuracy of 86.68% and specificity of 93.71% are reached. With the proposed method, automatic and accurate detection of seizures can be performed in real time, and the heavy burden of neurologists can be effectively reduced.

摘要

脑电图(EEG)是一种常用于癫痫诊断的临床方法,癫痫是一种危及生命的神经障碍。已经提出了许多使用传统机器学习和深度学习的算法来自动检测癫痫发作。尽管深度学习方法在许多领域取得了巨大的成功,但它们在 EEG 分析和分类中的性能仍然受到限制,主要是由于可用数据集的规模相对较小。在本文中,我们提出了一种基于深度度量学习的自动癫痫发作检测方法,这是一种通过减轻对大量数据的需求来解决小样本问题的新策略。首先,我们提出了两个一维卷积嵌入模块作为深度特征提取器,分别用于单通道和多通道 EEG 信号。然后,详细介绍了一种深度度量学习模型及其分阶段训练策略。在公开的波恩大学数据集上进行了实验,该数据集是一个基准数据集,以及更大和更现实的 CHB-MIT 数据集。在波恩数据集最难的分类(子集 D 与子集 E)中,我们达到了平均准确率为 98.60%和特异性为 100%的令人印象深刻的结果。在 CHB-MIT 数据集上,我们达到了平均准确率为 86.68%和特异性为 93.71%的结果。通过使用我们提出的方法,可以实时进行自动和准确的癫痫发作检测,有效减轻神经科医生的沉重负担。

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