Division of Cardiology, Columbia University Medical Center, New York, NY (M.I.B., A.M., V.G.N., R.T.H., S.K.K., G.T.S., N.U., D.B.).
Department of Internal Medicine, Justus Liebig Universitat Giessen, Germany (K.T.).
Circ Heart Fail. 2022 Jan;15(1):e009101. doi: 10.1161/CIRCHEARTFAILURE.121.009101. Epub 2021 Dec 29.
Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and diastolic properties independent of loading conditions like volume status and afterload. While long-considered the gold-standard method for quantifying myocardial chamber performance, it was traditionally only performed in highly specialized research settings. With recent advances in catheter technology and more sophisticated approaches to analyze PV data, it is now more commonly used in a variety of clinical and research settings. Herein, we review the basic techniques for PV loop measurement, analysis, and interpretation with the aim of providing readers with a deeper understanding of the strengths and limitations of PV analysis. In the second half of the review, we detail key scenarios in which right ventricular PV analysis has influenced our understanding of clinically relevant topics and where the technique can be applied to resolve additional areas of uncertainty. All told, PV analysis has an important role in advancing our understanding of right ventricular physiology and its contribution to cardiovascular function in health and disease.
右心室压力-容积（PV）分析可独立于容量状态和后负荷等负荷条件来描述心室收缩和舒张特性。虽然它长期以来被认为是量化心肌室性能的金标准方法，但传统上仅在高度专业化的研究环境中进行。随着导管技术的最新进展和更复杂的 PV 数据分析方法，它现在更常用于各种临床和研究环境。在此，我们回顾了 PV 环测量、分析和解释的基本技术，旨在为读者提供对 PV 分析的优势和局限性的更深入了解。在评论的后半部分，我们详细介绍了右心室 PV 分析影响我们对临床相关主题的理解的关键情况，以及该技术可应用于解决其他不确定性领域的情况。总的来说，PV 分析在推进我们对右心室生理学及其在健康和疾病中心血管功能中的贡献的理解方面发挥了重要作用。
