Department of Surgery, School of Medicine, Pamukkale University, Denizli, Turkey.
Department of Nephrology, School of Medicine, Pamukkale University, Denizli, Turkey.
BMC Surg. 2021 Dec 29;21(1):444. doi: 10.1186/s12893-021-01447-1.
Kidney transplantation is the most preferred type of renal displacement therapy for end stage renal disease (ESRD) patients. More patients developed ESRD. The most important source is the donations from unrelated spouses. In this study, we aimed to compare the transplantation data obtained from the spouses of the patients with the transplantation data obtained from other relatives.
The data including 167 living kidney transplantations performed between January 2006 and December 2019 were retrospectively collected. The patients were divided into two groups; spousal donor group (n: 53) and living-related donor group (n: 114).
There was no significant difference in delayed graft function in both groups. There were no patients with acute rejection proven by biopsy or considered biochemically in the spousal donor group. With regard to 3-year results in the living-related donor group the patient survival rate was 100%, while it was 98.2% in terms of graft survival.
In conclusion, similar patient and graft survival rates between spousal donor kidney transplantation and living-related kidney transplantation has made spousal donor kidney transplantation, with possible problems in terms of tissue compatibility, an acceptable alternative to donor supply.
肾移植是治疗终末期肾病（ESRD）患者的最优选肾替代疗法。越来越多的患者发展为 ESRD。最重要的供体来源是无血缘关系的配偶的捐赠。在这项研究中，我们旨在比较从患者配偶获得的移植数据与从其他亲属获得的移植数据。
回顾性收集了 2006 年 1 月至 2019 年 12 月期间进行的 167 例活体肾移植的数据。患者分为两组；配偶供体组（n：53）和活体亲属供体组（n：114）。
两组均无明显延迟移植物功能。配偶供体组无经活检证实或生化证实的急性排斥反应患者。在活体亲属供体组中，3 年的患者存活率为 100%，而移植物存活率为 98.2%。
总之，配偶供体肾移植与活体亲属肾移植之间相似的患者和移植物存活率使得配偶供体肾移植成为供体供应方面可能存在组织相容性问题的可接受替代方案。
