Chidlow J W, Porter P
Res Vet Sci. 1978 Mar;24(2):254-7.
Oral immunisation with Escherichia coli polysaccharide antigens provided a primary antigenic stimulus which facilitated the production of humoral IgM antibody following a single parenteral antigen dose. The peak antibody response of preparturient sows was manipulated to coincide with the period of colostrum formation so that high levels of IgM antibody were made available for neonatal defence. The characteristics of the immune response remained unchanged on reintroduction of the immunisation schedule for a second gestation period.
用大肠杆菌多糖抗原进行口服免疫可提供初次抗原刺激,这有助于在单次注射抗原后产生体液IgM抗体。对产前母猪的抗体反应峰值进行调控,使其与初乳形成期一致,以便有高水平的IgM抗体用于新生仔猪的防御。在第二个妊娠期重新采用免疫程序时,免疫反应的特征保持不变。