Department of Orthopaedics & Rehabilitation, Oregon Health & Science University, Sam Jackson Hall, Suite 2360, 3181 S.W. Sam Jackson Park Rd, Portland, OR 97239, USA.
Department of Orthopaedics & Rehabilitation, Oregon Health & Science University, Sam Jackson Hall, Suite 2360, 3181 S.W. Sam Jackson Park Rd, Portland, OR 97239, USA.
Spine J. 2022 May;22(5):810-818. doi: 10.1016/j.spinee.2021.12.012. Epub 2021 Dec 25.
Almost half of all patients undergoing lumbar spine surgery have preoperative lower urinary tract symptoms (LUTS). These symptoms could affect postoperative voiding and subsequently length of stay.
To investigate the association between preoperative LUTS and time to first void and between time to first void and time to discharge among patients undergoing elective lumbar decompression surgery.
STUDY DESIGN/SETTING: Retrospective analysis of prospectively collected data among patients at a single academic medical center.
All patients ≥18 years of age undergoing elective lumbar decompression surgery between July 2017 and March 2020.
The physiologic measure of a delayed time to first void was defined as an initial postoperative void of > 4 hours after anesthesia stop time. The outcome of prolonged time to discharge was defined as a stay of >24 hours after anesthesia stop time.
At their preoperative visit, patients completed the validated International Prostate Symptom Score (IPSS) (range, 0-35 points), which is applicable for LUTS assessment in both sexes. Clinically relevant LUTS are defined as an IPSS score of ≥8. Patients were followed from their preoperative visit to surgery admission discharge. Association of LUTS with time to first void and time to first void with admission discharge were estimated using risk ratios (RR) and 95% confidence intervals (CI) from a multivariable Poisson regression with a robust variance estimate adjusted for potential confounding variables including age, sex, IPSS, and intraoperative Foley catheter use.
The analytic cohort included 170 patients with an average age of 57 years and 103 (61%) were men. Preoperative LUTS prevalence was 45%, and 111 (65%) of patients voided within 4 hours after surgery. For patients with preoperative LUTS, the unadjusted RR for a first void of >4 hours was 1.04 (95% CI: 0.82-1.32) (p=.77). Adjustment for age, sex, intraoperative Foley catheter use, revision surgery, previous spine surgery, single versus multiple levels, and lumbar location did not materially alter the risk: the multivariable RR was 1.04 (95% CI: 0.82-1.31) (p=.74). The unadjusted RR for a discharge of > 24 hours for patients with a time to first void of > 4 hours was 2.17 (95% CI: 1.51-3.10) (p<.001). After adjusting for age, sex, intraoperative Foley catheter use, IPSS, revision surgery, previous spine surgery, single versus multiple levels, and lumbar location, the multivariable RR was 1.72 (95% CI: 1.22-2.41) (p=.002).
Regardless of preoperative LUTS status, an initial first void of >4 hours after surgery is associated with a longer time to discharge among patients undergoing elective lumbar decompression surgery. Future studies are needed to determine if encouraging early postoperative voiding results in timely discharge and shorter length of stay.
将近一半接受腰椎手术的患者术前有下尿路症状(LUTS)。这些症状可能会影响术后排尿,进而影响住院时间。
研究术前 LUTS 与首次排尿时间之间的关系,以及首次排尿时间与腰椎减压手术患者出院时间之间的关系。
研究设计/设置:单中心前瞻性收集数据的回顾性分析。
2017 年 7 月至 2020 年 3 月期间在单家学术医疗中心接受择期腰椎减压手术的所有年龄≥18 岁的患者。
首次排尿延迟的生理指标定义为麻醉停止后 4 小时以上的初始术后排尿。延长出院时间的结果定义为麻醉停止后 24 小时以上的住院时间。
在术前就诊时,患者完成了经过验证的国际前列腺症状评分(IPSS)(范围为 0-35 分),该评分适用于男女的 LUTS 评估。临床相关的 LUTS 定义为 IPSS 评分≥8 分。患者从术前就诊到手术入院到出院进行随访。使用多变量泊松回归(具有稳健方差估计),调整潜在混杂变量(包括年龄、性别、IPSS 和术中 Foley 导管使用),估计 LUTS 与首次排尿时间以及首次排尿时间与入院出院时间之间的关系,使用风险比(RR)和 95%置信区间(CI)。
分析队列包括 170 名平均年龄 57 岁的患者,其中 103 名(61%)为男性。术前 LUTS 的患病率为 45%,111 名(65%)患者在术后 4 小时内排尿。对于术前有 LUTS 的患者,首次排尿>4 小时的未调整 RR 为 1.04(95%CI:0.82-1.32)(p=.77)。调整年龄、性别、术中 Foley 导管使用、翻修手术、既往脊柱手术、单节段与多节段以及腰椎位置后,风险无明显变化:多变量 RR 为 1.04(95%CI:0.82-1.31)(p=.74)。对于首次排尿>4 小时的患者,首次排尿时间>4 小时与出院时间>24 小时的未调整 RR 为 2.17(95%CI:1.51-3.10)(p<.001)。在调整年龄、性别、术中 Foley 导管使用、IPSS、翻修手术、既往脊柱手术、单节段与多节段以及腰椎位置后,多变量 RR 为 1.72(95%CI:1.22-2.41)(p=.002)。
无论术前 LUTS 状况如何,腰椎减压手术后首次排尿>4 小时与患者出院时间延长有关。未来的研究需要确定是否鼓励术后早期排尿可导致及时出院和缩短住院时间。