新型含两个吖啶单元的可聚合四氮杂大环化合物用于金属离子的选择性荧光传感。

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért tér 4, 1111, Budapest, Hungary.

Institute for Energy Security and Environmental Safety, Centre for Energy Research, Konkoly-Thege Miklós út 29-33, 1121, Budapest, Hungary.

J Fluoresc. 2022 Mar;32(2):473-481. doi: 10.1007/s10895-021-02851-9. Epub 2021 Dec 29.

A new fluorescent bis(acridino)-macrocycle containing two allyl groups was synthesized and photophysically studied. Studies were carried out on metal ion recognition and selectivity-influencing effects including the determination of the relevant thermodynamic constants as logK and pK. The proposed sensor molecule is recommended for the development of Zn-selective optochemical analyzers based on covalently immobilized ionophores as it has a unique pH-independent metal ion recognition ability, which is not influenced by anions and other potentially occurring metal ions in biological samples.

合成了一种新型含两个烯丙基的荧光双（吖啶）大环，并对其光物理性质进行了研究。研究了金属离子识别和选择性影响效应，包括相关热力学常数如 logK 和 pK 的测定。鉴于该传感器分子具有独特的 pH 非依赖性金属离子识别能力，不受生物样品中阴离子和其他潜在存在的金属离子的影响，因此建议将其用于开发基于共价固定化离子载体的 Zn 选择性光化学分析仪。